Breast cancer (BC) is the most-frequent malignancy amongst women, whereas obesity and
excess caloric consumption increase the risk for developing the disease. The objective of …

Simple Summary Pancreatic ductal adenocarcinoma is a devastating disease that is very
hard to treat. Here, we advance and evaluate the notion that the best possible management …

Background Ketogenic diet is a potential means of augmenting cancer therapy. Here, we
explore ketone body metabolism and its interplay with chemotherapy in pancreatic cancer …

Intermittent fasting entails restricting food intake during specific times of day, days of the
week, religious practice, or surrounding clinically important events. Herein, the metabolic …

Being overweight or obese (OW/OB) during B-cell acute lymphoblastic leukemia (B-ALL)
induction is associated with chemoresistance as quantified by minimal residual disease …

Dietary restriction and fasting have been recognized for their beneficial effects on health and
lifespan and their potential application in managing chronic metabolic diseases. However …

Simple Summary The insulin-like growth factor-1 receptor (IGF1R) is a receptor commonly
overexpressed and overactivated in a variety of cancers, including Ewing sarcoma, and …

Context Breast cancer is a significant public health challenge, with 290 000 new cases
annually and significant healthcare costs. Treatment advancements have led to …

Genotoxic agents such as doxorubicin (DXR) can cause damage to the intestines that can
be ameliorated by fasting. How fasting is protective and the optimal timing of fasting and …

Background & aims Experimental studies in cancer cell lines and tumour-bearing animals
support the concept that a short-period fasting could potentiate the effect of antineoplastic …