Th1 and Th17 cells in tuberculosis: protection, pathology, and biomarkers
IV Lyadova, AV Panteleev - Mediators of inflammation, 2015 - Wiley Online Library
The outcome of Mycobacterium tuberculosis (Mtb) infection ranges from a complete
pathogen clearance through asymptomatic latent infection (LTBI) to active tuberculosis (TB) …
pathogen clearance through asymptomatic latent infection (LTBI) to active tuberculosis (TB) …
Mycobacterium tuberculosis-specific cytokine biomarkers to differentiate active TB and LTBI: a systematic review
Objectives New tests are needed to overcome the limitations of existing immunodiagnostic
tests for tuberculosis (TB) infection, including their inability to differentiate between active TB …
tests for tuberculosis (TB) infection, including their inability to differentiate between active TB …
Transcriptional analysis of human peripheral blood mononuclear cells stimulated by Mycobacterium tuberculosis antigen
J Wei, F Guo, Y Song, K Xu, F Lin, K Li, B Li… - Frontiers in Cellular …, 2023 - frontiersin.org
Background Mycobacterium tuberculosis antigen (Mtb-Ag) is a polypeptide component with
a molecular weight of 10-14 kDa that is obtained from the supernatant of the H37Ra strain …
a molecular weight of 10-14 kDa that is obtained from the supernatant of the H37Ra strain …
Cytokine biomarkers for the diagnosis of tuberculosis infection and disease in adults in a low prevalence setting
V Clifford, M Tebruegge, C Zufferey, S Germano… - Tuberculosis, 2019 - Elsevier
Objective Accurate and timely diagnosis of tuberculosis (TB) is essential to control the global
pandemic. Currently available immunodiagnostic tests cannot discriminate between latent …
pandemic. Currently available immunodiagnostic tests cannot discriminate between latent …
[HTML][HTML] An IFN-γ and TNF-α dual release fluorospot assay for diagnosing active tuberculosis
JY Kim, YA Kang, JH Park, HH Cha, NY Jeon… - Clinical Microbiology …, 2020 - Elsevier
Objectives Currently available interferon (IFN)-γ-release assays (IGRA) cannot discriminate
active tuberculosis (TB) from latent TB infection (LTBI), and so have limited clinical utility for …
active tuberculosis (TB) from latent TB infection (LTBI), and so have limited clinical utility for …
Combined IFN-γ and TNF-α release assay for differentiating active tuberculosis from latent tuberculosis infection
JY Kim, JH Park, MC Kim, HH Cha, NY Jeon, SY Park… - Journal of Infection, 2018 - Elsevier
Objectives The IFN-γ-release assay (IGRA) cannot differentiate active tuberculosis (TB) from
latent TB infection (LTBI). We hypothesized that the TNF-α-release assay (TARA) combined …
latent TB infection (LTBI). We hypothesized that the TNF-α-release assay (TARA) combined …
[HTML][HTML] Potential of the dual IFN-γ/IL-2 fluorescence-immunospot assay to distinguish different stages in bovine tuberculosis
S Steinbach, HM Vordermeier, GJ Jones - Veterinary immunology and …, 2019 - Elsevier
Human studies have identified the potential of measuring Mycobacterium tuberculosis
specific IFN-γ and/or IL-2 secreting T cell subsets to distinguish different clinical stages of …
specific IFN-γ and/or IL-2 secreting T cell subsets to distinguish different clinical stages of …
Utility of Th1-cell immune responses for distinguishing active tuberculosis from non-active tuberculosis: a case-control study
L Zhang, X Cheng, S Bian, Y Song, Q Li, M Gao… - PLoS …, 2017 - journals.plos.org
Currently available Interferon-γ release assay (IGRA) cannot reliably differentiate active TB
(ATB) from non-active TB (non-ATB). A study was performed to evaluate the value of …
(ATB) from non-active TB (non-ATB). A study was performed to evaluate the value of …
Maintenance of Mycobacterium tuberculosis-specific T cell responses in End Stage Renal Disease (ESRD) and implications for diagnostic efficacy
End-stage renal disease (ESRD) patients exhibit elevated risk of tuberculosis (TB)
reactivation, but current diagnostics, including the interferon gamma release assay (IGRA) …
reactivation, but current diagnostics, including the interferon gamma release assay (IGRA) …
Иммунокоррекция в комплексном лечении туберкулеза легких
СН Демидик, СБ Вольф - 2016 - elibrary.ru
В монографии обобщены современные данные об особенностях иммунного ответа
при туберкулезной инфекции, а также роли цитокинов в иммунопатогенезе …
при туберкулезной инфекции, а также роли цитокинов в иммунопатогенезе …