Sarcopenia and cardiovascular diseases

AA Damluji, M Alfaraidhy, N AlHajri, NN Rohant… - Circulation, 2023 - Am Heart Assoc
Sarcopenia is the loss of muscle strength, mass, and function, which is often exacerbated by
chronic comorbidities including cardiovascular diseases, chronic kidney disease, and …

Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

R Sartori, V Romanello, M Sandri - Nature communications, 2021 - nature.com
Skeletal muscle is the protein reservoir of our body and an important regulator of glucose
and lipid homeostasis. Consequently, the growth or the loss of muscle mass can influence …

[HTML][HTML] Selective autophagy of intracellular organelles: recent research advances

W Li, P He, Y Huang, YF Li, J Lu, M Li, H Kurihara… - Theranostics, 2021 - ncbi.nlm.nih.gov
Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and …

Mechanisms of IGF-1-mediated regulation of skeletal muscle hypertrophy and atrophy

T Yoshida, P Delafontaine - Cells, 2020 - mdpi.com
Insulin-like growth factor-1 (IGF-1) is a key growth factor that regulates both anabolic and
catabolic pathways in skeletal muscle. IGF-1 increases skeletal muscle protein synthesis via …

Associated factors of sarcopenia in community-dwelling older adults: a systematic review and meta-analysis

Q Gao, K Hu, C Yan, B Zhao, F Mei, F Chen, L Zhao… - Nutrients, 2021 - mdpi.com
(1) Background: To review the associated factors of sarcopenia in community-dwelling older
adults.(2) Methods: PubMed, Embase, Web of Science, and four Chinese electronic …

Skeletal muscle atrophy: From mechanisms to treatments

L Yin, N Li, W Jia, N Wang, M Liang, X Yang… - Pharmacological …, 2021 - Elsevier
Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …

Cancer-associated cachexia

VE Baracos, L Martin, M Korc, DC Guttridge… - Nature reviews Disease …, 2018 - nature.com
Cancer-associated cachexia is a disorder characterized by loss of body weight with specific
losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination …

Mitochondrial dysfunction: roles in skeletal muscle atrophy

X Chen, Y Ji, R Liu, X Zhu, K Wang, X Yang… - Journal of Translational …, 2023 - Springer
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle
health, and damage to mitochondria can lead to a series of pathophysiological changes …

Growth hormone (s), testosterone, insulin-like growth factors, and cortisol: roles and integration for cellular development and growth with exercise

WJ Kraemer, NA Ratamess, WC Hymer… - Frontiers in …, 2020 - frontiersin.org
Hormones are largely responsible for the integrated communication of several physiological
systems responsible for modulating cellular growth and development. Although the specific …

Autophagy in ischemic stroke

P Wang, BZ Shao, Z Deng, S Chen, Z Yue… - Progress in …, 2018 - Elsevier
Autophagy is a self-eating cellular catabolic pathway, through which long-lived proteins,
damaged organelles and misfolded proteins are degraded and recycled for the …