Brain-derived neurotrophic factor in brain disorders: focus on neuroinflammation

B Lima Giacobbo, J Doorduin, HC Klein… - Molecular …, 2019 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates …

The “posture second” strategy: a review of wrong priorities in Parkinson's disease

BR Bloem, YAM Grimbergen, JG van Dijk… - Journal of the …, 2006 - Elsevier
Falls are common in Parkinson's disease. It remains difficult to predict these falls,
presumably because clinical balance tests assess single components of postural control …

Healthrelated quality of life in early Parkinson's disease: The impact of nonmotor symptoms

GW Duncan, TK Khoo, AJ Yarnall… - Movement …, 2014 - Wiley Online Library
Nonmotor symptoms (NMS) are common in patients with established Parkinson's disease
(PD) and have a major impact upon quality of life. We investigated the significance of NMS …

Depression and anxiety in Parkinson's disease

A Schrag, RN Taddei - International review of neurobiology, 2017 - Elsevier
Depression and anxiety are some of the most common comorbidities arising in patients with
Parkinson's disease. However, their timely recognition and diagnosis are often hindered by …

Reprint of “Neuropsychiatric symptoms, behavioural disorders, and quality of life in Parkinson's disease”

R Balestrino, P Martinez-Martin - Journal of the neurological sciences, 2017 - Elsevier
Parkinson's disease is a complex neurodegenerative disorder characterized by motor and
non-motor symptoms, with neuropsychiatric manifestations among the most frequent non …

Predictors of health-related quality of life in Parkinson's disease

GD Kuhlman, JL Flanigan, SA Sperling… - Parkinsonism & related …, 2019 - Elsevier
Background Health-related quality of life in Parkinson's disease may be affected by a wide
range of motor and non-motor symptoms. Identifying which symptoms are significant …

Brain-derived neurotrophic factor: a novel dynamically regulated therapeutic modulator in neurological disorders

V Sharma, TG Singh, A Kaur, A Mannan… - Neurochemical …, 2023 - Springer
The growth factor brain-derived neurotrophic factor (BDNF), and its receptor tropomyosin-
related kinase receptor type B (TrkB) play an active role in numerous areas of the adult …

[HTML][HTML] Anxiety: An ignored aspect of Parkinson's disease lacking attention

DK Khatri, M Choudhary, A Sood, SB Singh - Biomedicine & …, 2020 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disease which affects millions
of population worldwide. It is characterized by motor symptoms such as excessive tremor …

Health-related quality of life in Parkinson's disease: a cross-sectional study focusing on non-motor symptoms

L Kadastik-Eerme, M Rosenthal, T Paju… - Health and quality of life …, 2015 - Springer
Background The objective of this study was to investigate factors affecting health-related
quality of life (HRQoL) among Estonian persons with Parkinson's disease (PD). Methods …

The high prevalence of impulse control behaviors in patients with early-onset Parkinson's disease: a cross-sectional multicenter study

L Vela, JCM Castrillo, PG Ruiz, C Gasca-Salas… - Journal of the …, 2016 - Elsevier
Abstract Introduction In Parkinson's disease patients, impulse control disorders (ICDs) have
been associated with younger age and early disease onset, yet the prevalence of ICDs in …