Cross-feeding in the gut microbiome: ecology and mechanisms

EJ Culp, AL Goodman - Cell host & microbe, 2023 - cell.com
Microbial communities are shaped by positive and negative interactions ranging from
competition to mutualism. In the context of the mammalian gut and its microbial inhabitants …

The ecological roles of bacterial chemotaxis

JM Keegstra, F Carrara, R Stocker - Nature Reviews Microbiology, 2022 - nature.com
How bacterial chemotaxis is performed is much better understood than why. Traditionally,
chemotaxis has been understood as a foraging strategy by which bacteria enhance their …

Inter-bacterial mutualism promoted by public goods in a system characterized by deterministic temperature variation

Y Zhao, Z Liu, B Zhang, J Cai, X Yao, M Zhang… - Nature …, 2023 - nature.com
Mutualism is commonly observed in nature but not often reported for bacterial communities.
Although abiotic stress is thought to promote microbial mutualism, there is a paucity of …

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

A Luengo, Z Li, DY Gui, LB Sullivan, M Zagorulya… - Molecular cell, 2021 - cell.com
Aerobic glycolysis, or preferential fermentation of glucose-derived pyruvate to lactate despite
available oxygen, is associated with proliferation across many organisms and conditions. To …

Trophic interactions and the drivers of microbial community assembly

M Gralka, R Szabo, R Stocker, OX Cordero - Current Biology, 2020 - cell.com
Despite numerous surveys of gene and species content in heterotrophic microbial
communities, such as those found in animal guts, oceans, or soils, it is still unclear whether …

Strength of species interactions determines biodiversity and stability in microbial communities

C Ratzke, J Barrere, J Gore - Nature ecology & evolution, 2020 - nature.com
Organisms—especially microbes—tend to live together in ecosystems. While some of these
ecosystems are very biodiverse, others are not, and while some are very stable over time …

Emergent simplicity in microbial community assembly

JE Goldford, N Lu, D Bajić, S Estrela, M Tikhonov… - Science, 2018 - science.org
A major unresolved question in microbiome research is whether the complex taxonomic
architectures observed in surveys of natural communities can be explained and predicted by …

Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance

JSL Yu, C Correia-Melo, F Zorrilla… - Nature …, 2022 - nature.com
Microbial communities are composed of cells of varying metabolic capacity, and regularly
include auxotrophs that lack essential metabolic pathways. Through analysis of auxotrophs …

The Warburg effect: how does it benefit cancer cells?

MV Liberti, JW Locasale - Trends in biochemical sciences, 2016 - cell.com
Cancer cells rewire their metabolism to promote growth, survival, proliferation, and long-term
maintenance. The common feature of this altered metabolism is the increased glucose …

A universal trade-off between growth and lag in fluctuating environments

M Basan, T Honda, D Christodoulou, M Hörl, YF Chang… - Nature, 2020 - nature.com
The rate of cell growth is crucial for bacterial fitness and drives the allocation of bacterial
resources, affecting, for example, the expression levels of proteins dedicated to metabolism …