The Martini model, a coarse‐grained force field for molecular dynamics simulations, has
been around for nearly two decades. Originally developed for lipid‐based systems by the …

In the last decade, molecular dynamics (MD) simulations have become an essential tool to
investigate the molecular properties of membrane trafficking processes, often in conjunction …

Myomerger is a muscle-specific membrane protein involved in formation of multinucleated
muscle cells by mediating the transition from the early hemifusion stage to complete fusion …

The Golgi complex is the membrane-bound organelle that lies at the center of the secretory
pathway. Its main functions are to maintain cellular lipid homeostasis, to orchestrate protein …

Eukaryotic cells contain membranes with various curvatures, from the near-plane plasma
membrane to the highly curved membranes of organelles, vesicles, and membrane …

Highlights•Molecular dynamics simulations are the central technique uniting the field of
computational virology.•Viruses responsible for recent epidemics and pandemics have been …

Viral infections, fertilization, neurotransmission, and many other fundamental biological
processes rely on membrane fusion. Straightforward calculations based on the celebrated …

Multiple recent reports indicate that the S protein of SARS-CoV-2 specifically interacts with
membrane receptors and attachment factors other than ACE2. They likely have an active …

Cellular distributions of the sphingolipid ceramide-1-phosphate (C1P) impact essential
biological processes. C1P levels are spatiotemporally regulated by ceramide-1-phosphate …

To infect a cell, enveloped viruses must first undergo membrane fusion, which proceeds
through a hemifusion intermediate, followed by the formation of a fusion pore through which …