Drugs for insomnia beyond benzodiazepines: pharmacology, clinical applications, and discovery

T Atkin, S Comai, G Gobbi, EL Barker - Pharmacological reviews, 2018 - Elsevier
Abstract Although the GABAergic benzodiazepines (BZDs) and Z-drugs (zolpidem,
zopiclone, and zaleplon) are FDA-approved for insomnia disorders with a strong evidence …

Review of safety and efficacy of sleep medicines in older adults

JL Schroeck, J Ford, EL Conway, KE Kurtzhalts… - Clinical …, 2016 - Elsevier
Purpose Insomnia is problematic for older adults. After behavioral modifications fail to show
adequate response, pharmacologic options are used. The pharmacokinetics of agents used …

Alcohol use disorder and sleep disturbances: a feed-forward allostatic framework

GF Koob, IM Colrain - Neuropsychopharmacology, 2020 - nature.com
The development of alcohol use disorder (AUD) involves binge or heavy drinking to high
levels of intoxication that leads to compulsive intake, the loss of control in limiting intake, and …

Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review

GA Angarita, N Emadi, S Hodges… - Addiction science & clinical …, 2016 - Springer
Sleep abnormalities are associated with acute and chronic use of addictive substances.
Although sleep complaints associated with use and abstinence from addictive substances …

Efficacy of gabapentin for the treatment of alcohol use disorder in patients with alcohol withdrawal symptoms: a randomized clinical trial

RF Anton, P Latham, K Voronin, S Book… - JAMA internal …, 2020 - jamanetwork.com
Importance Although an estimated 30 million people meet criteria for alcohol use disorder
(AUD), few receive appropriate pharmacotherapy. A more personalized, symptom-specific …

Alcohol dependence and its relationship with insomnia and other sleep disorders

S Chakravorty, NS Chaudhary… - Alcoholism: Clinical and …, 2016 - Wiley Online Library
Sleep‐related complaints are widely prevalent in those with alcohol dependence (AD). AD is
associated not only with insomnia, but also with multiple sleep‐related disorders as a …

[HTML][HTML] Trazodone for insomnia: a systematic review

KY Jaffer, T Chang, B Vanle, J Dang… - Innovations in clinical …, 2017 - ncbi.nlm.nih.gov
OBJECTIVE: While trazodone is approved for the treatment of depression, the off-label use
of this medication for insomnia has surpassed its usage as an antidepressant. In this …

Manual of clinical psychopharmacology

AF Schatzberg, JO Cole, C DeBattista - Washington, DC, 2003 - psychiatrist.com
Welcome to the fifth edition of a very handy and useful book, the Manual of Clinical
Psychopharmacology. Readers familiar with any of the previous editions are already aware …

Gabapentin for the treatment of alcohol use disorder

BJ Mason, S Quello, F Shadan - Expert opinion on investigational …, 2018 - Taylor & Francis
Introduction: Alcohol misuse is the fifth leading risk factor for premature death and disability
worldwide. Fewer than 10% of afflicted Americans receive pharmacological treatment for …

Anticonvulsants for alcohol withdrawal

S Minozzi, L Amato, S Vecchi… - Cochrane database of …, 2010 - cochranelibrary.com
Background Alcohol abuse and dependence represents a most serious health problem
worldwide with major social, interpersonal and legal interpolations. Besides …