Simple Summary Environmental conditions are subject to unprecedented changes due to
recent progressive anthropogenic activities on our planet. Plants, as the frontline of food …

Tocopherols and tocotrienols are natural compounds of plant origin, available in the nature.
They are supplied in various amounts in a diet, mainly from vegetable oils, some oilseeds …

Free radicals are generated in our body by several systems. A balance among free radicals
and antioxidants is an important matter for appropriate physiological function. If free radicals …

Reactive oxygen species (ROS) are generated as by-products of normal cellular metabolic
activities. Superoxide dismutase, glutathione peroxidase, and catalase are the enzymes …

The discovery of vitamin E will have its 100th anniversary in 2022, but we still have more
questions than answers regarding the biological functions and the essentiality of vitamin E …

Multiple reactive oxygen/nitrogen species induce oxidative stress. Mammals have evolved
with an elaborate defense network against oxidative stress, in which multiple antioxidant …

Four tocopherols are available in nature and are absorbed with the diet, but only one RRR-α-
tocopherol satisfies the criteria of being a vitamin. The biological activity of the different …

Oxidative stress has been implicated in the pathogenesis of diverse disease states, and may
be a common pathogenic mechanism underlying many major psychiatric disorders, as the …

This comprehensive narrative review summarizes relevant antioxidant mechanisms, the
antioxidant status, and effects of supplementation in critically ill patients for the most studied …

Oxidative stress is a key component in linking environmental toxicity to the multistage
carcinogenic process. Reactive oxygen species (ROS) are generated in response to both …