Lessons from the host defences of bats, a unique viral reservoir
There have been several major outbreaks of emerging viral diseases, including Hendra,
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …
The science underlying COVID-19: implications for the cardiovascular system
The coronavirus disease 2019 (COVID-19) pandemic has affected health and economy
worldwide on an unprecedented scale. Patients have diverse clinical outcomes, but those …
worldwide on an unprecedented scale. Patients have diverse clinical outcomes, but those …
[HTML][HTML] Zoonotic origins of human coronaviruses
ZW Ye, S Yuan, KS Yuen, SY Fung… - International journal of …, 2020 - ncbi.nlm.nih.gov
Mutation and adaptation have driven the co-evolution of coronaviruses (CoVs) and their
hosts, including human beings, for thousands of years. Before 2003, two human CoVs …
hosts, including human beings, for thousands of years. Before 2003, two human CoVs …
A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses
SY Fung, KS Yuen, ZW Ye, CP Chan… - Emerging microbes & …, 2020 - Taylor & Francis
ABSTRACT World Health Organization has declared the ongoing outbreak of coronavirus
disease 2019 (COVID-19) a Public Health Emergency of International Concern. The virus …
disease 2019 (COVID-19) a Public Health Emergency of International Concern. The virus …
Bat-borne virus diversity, spillover and emergence
Most viral pathogens in humans have animal origins and arose through cross-species
transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus …
transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus …
Bats and coronaviruses
Bats are speculated to be reservoirs of several emerging viruses including coronaviruses
(CoVs) that cause serious disease in humans and agricultural animals. These include CoVs …
(CoVs) that cause serious disease in humans and agricultural animals. These include CoVs …
Decoding type I and III interferon signalling during viral infection
EV Mesev, RA LeDesma, A Ploss - Nature microbiology, 2019 - nature.com
Interferon (IFN)-mediated antiviral responses are central to host defence against viral
infection. Despite the existence of at least 20 IFNs, there are only three known cell surface …
infection. Despite the existence of at least 20 IFNs, there are only three known cell surface …
Novel insights into immune systems of bats
In recent years, viruses similar to those that cause serious disease in humans and other
mammals have been detected in apparently healthy bats. These include filoviruses …
mammals have been detected in apparently healthy bats. These include filoviruses …
[HTML][HTML] Binding and molecular basis of the bat coronavirus RaTG13 virus to ACE2 in humans and other species
K Liu, X Pan, L Li, F Yu, A Zheng, P Du, P Han, Y Meng… - Cell, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been spreading
worldwide, causing a global pandemic. Bat-origin RaTG13 is currently the most …
worldwide, causing a global pandemic. Bat-origin RaTG13 is currently the most …
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
Bats are special in their ability to host emerging viruses. As the only flying mammal, bats
endure high metabolic rates yet exhibit elongated lifespans. It is currently unclear whether …
endure high metabolic rates yet exhibit elongated lifespans. It is currently unclear whether …