Protein glycosylation is a ubiquitous post-translational modification found in all domains of
life. Despite their significant complexity in animal systems, glycan structures have crucial …

Advances in nuclease-based gene-editing technologies have enabled precise, stable, and
systematic genetic engineering of glycosylation capacities in mammalian cells, opening up a …

Glycosylation is a ubiquitous modification that occurs on proteins and lipids in all living cells.
Consistent with their high complexity, glycans play crucial biological roles in protein quality …

The glycocalyx comprises glycosylated proteins and lipids and fcorms the outermost layer of
cells. It is involved in fundamental inter-and intracellular processes, including non-self-cell …

Glycans on proteins and lipids are known to alter with malignant transformation. The study of
these may contribute to the discovery of biomarkers and treatment targets as well as …

Although many of the frequently used pluripotency biomarkers are glycoconjugates, a
glycoconjugate-based exploration of novel cellular biomarkers has proven difficult due to …

Cell membranes are key interfaces where materials engineering meets biology. Traditionally
regarded as just the location of receptors regulating the uptake of molecules, we now know …

The detailed examination of enzyme molecules by mass spectrometry and other techniques
continues to identify hundreds of distinct PTMs. Recently, global analyses of enzymes using …

Epithelial ovarian cancer is one of the most fatal gynecological malignancies in adult
women. As studies on protein N‐glycosylation have extensively reported aberrant patterns …

Various cancers such as colorectal cancer (CRC) are associated with alterations in protein
glycosylation. CRC cell lines are frequently used to study these (glyco) biological changes …