Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …

Microtubule nucleation is regulated by the γ-tubulin ring complex (γTuRC) and related γ-
tubulin complexes, providing spatial and temporal control over the initiation of microtubule …

The highly conserved protein γ-tubulin is required for microtubule nucleation in vivo. When
viewed in the electron microscope, a highly purified γtubulin complex from Xenopus …

Fluorescence in situ hybridization (FISH) shows that fission yeast centromeres and
telomeres make up specific spatial arrangements in the nucleus. Their positioning and …

The novel concept of a centrosomal anchoring complex, which is distinct from the γ-tubulin
nucleating complex, has previously been proposed following studies on cochlear epithelial …

Nek2, a mammalian protein kinase of unknown function, is closely related to the mitotic
regulator NIMA of Aspergillus nidulans. Here we show by both immunofluorescence …

The centrosome nucleates microtubule polymerization, affecting mkrotubule number,
polarity, and structure. We use an in vitro system based on extmcts of Xenopus eggs to …

Spindle formation in fission yeast occurs by the interdigitation of two microtubule arrays
extending from duplicated spindle pole bodies which span the nuclear membrane. By …

γ-tubulin exists in two related complexes in Drosophila embryo extracts (Moritz, M., Y.
Zheng, BM Alberts, and K. Oegema. 1998. J. Cell Biol. 142: 1–12). Here, we report the …

ABSTRACT γ-Tubulin, a recently discovered member of the tubulin superfamily, is a peri-
centriolar component considered to be essential for microtubule nucleation. Mouse oocytes …