Recent advances in nanoparticle-mediated antibacterial applications

S Roy, I Hasan, B Guo - Coordination Chemistry Reviews, 2023 - Elsevier
Misuse and overuse of antibiotics led us vulnerable to multi-drug resistant (MDR) bacteria,
biofilms, and intracellular infections. The failure of conventional antibiotics thus gives rise to …

Antimicrobial peptides grafted onto the surface of N-acetylcysteine-chitosan nanoparticles can revitalize drugs against clinical isolates of Mycobacterium tuberculosis

LMDG Primo, CA Roque-Borda, CSC Canales… - Carbohydrate …, 2024 - Elsevier
Tuberculosis is caused by Mycobacterium tuberculosis (MTB) and is the leading cause of
death from infectious diseases in the World. The search for new antituberculosis drugs is a …

Roles of extracellular vesicles on macrophages in inflammatory bone diseases

Y Lin, Z Wang, S Liu, J Liu, Z Zhang, Y Ouyang… - Molecular and Cellular …, 2024 - Springer
Inflammatory bone disease is a general term for a series of diseases caused by chronic
inflammation, which leads to the destruction of bone homeostasis, that is, the osteolytic …

Natural antibacterial agent-based nanoparticles for effective treatment of intracellular MRSA infection

X Zou, S Cai, T Wang, S Zheng, X Cui, J Hao, X Chen… - Acta Biomaterialia, 2023 - Elsevier
Intracellular MRSA is extremely difficult to eradicate by traditional antibiotics, leading to
infection dissemination and drug resistance. A general lack of facile and long-term strategies …

Two-dimensional Nb2C-based nanoplatform augmented sonodynamic antibacterial therapy and bone regeneration

L Ma, X Zhang, H Wang, X Feng, J Lei, Y He… - Science China …, 2023 - Springer
Rapid disinfection and promotion of bone regeneration are two crucial aspects of the clinical
treatment of osteomyelitis. There is an urgent need to develop highly efficient bioactive …

Biomimetic Metal–Organic Framework Gated Nanoplatform for Sonodynamic Therapy against Extensively Drug Resistant Bacterial Lung Infection

J Huang, X Hong, S Chen, Y He, L Xie, F Gao… - Advanced …, 2024 - Wiley Online Library
Novel antimicrobial strategies are urgently needed to treat extensively drug‐resistant (XDR)
bacterial infections due to the high mortality rate and lack of effective therapeutic agents …

Supramolecular self‐assembled nanoparticles for targeted therapy of myocardial infarction by enhancing cardiomyocyte mitophagy

Y Jiao, H Wang, X Weng, J Wang, Y Li, J Shen… - …, 2024 - Wiley Online Library
Myocardial infarction accompanied by diabetes mellitus is accepted as the most serious type
of coronary heart disease, and among the current treatment strategies, the precise delivery …

Unraveling the in vivo biological fate of mPEG2000-PDLLA2500-COOH diblock copolymers by LC-MS/MS based on CID in source technique

M Shi, X Zheng, H Jiang, Y Ge, N Zhang, X Duan… - Analytica Chimica …, 2023 - Elsevier
Methoxy poly (ethylene glycol)-poly (D, L-lactic acid)(mPEG-PDLLA) is a biocompatible and
amphiphilic diblock copolymer composed of a hydrophilic poly (ethylene glycol) block and a …

Rifampicin-Loaded Polyelectrolyte Complex Eliminates Intracellular Bacteria through Thiol-Mediated Cellular Uptake and Oxidative Stress Enhancement

Z Xia, Y Liao, G Gao, S Zhang - ACS Applied Bio Materials, 2024 - ACS Publications
The poor accumulation of antibiotics in the cytoplasm leads to the poor eradication of
intracellular bacteria. Herein, a polyelectrolyte complex (PECs@ Rif) allowing direct …

[HTML][HTML] Regulating the microenvironment with nanomaterials: Potential strategies to ameliorate COVID-19

Z Liu, Z Han, X Jin, J An, J Kim, W Chen, JS Kim… - … Pharmaceutica Sinica B, 2023 - Elsevier
Abstract COVID-19, caused by SARS-CoV-2, has resulted in serious economic and health
burdens. Current treatments remain inadequate to extinguish the epidemic, and efficient …