The role of bile acids in carcinogenesis

T Režen, D Rozman, T Kovács, P Kovács… - Cellular and molecular …, 2022 - Springer
Bile acids are soluble derivatives of cholesterol produced in the liver that subsequently
undergo bacterial transformation yielding a diverse array of metabolites. The bulk of bile …

Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions

R Bouillon, C Marcocci, G Carmeliet, D Bikle… - Endocrine …, 2019 - academic.oup.com
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Bile acid signaling in inflammatory bowel diseases

S Fiorucci, A Carino, M Baldoni, L Santucci… - Digestive Diseases and …, 2021 - Springer
Bile acids are a group of chemically different steroids generated at the host/microbial
interface. Indeed, while primary bile acids are the end-product of cholesterol breakdown in …

Vitamin D supplementation guidelines for general population and groups at risk of vitamin D deficiency in Poland—recommendations of the polish society of pediatric …

A Rusińska, P Płudowski, M Walczak… - Frontiers in …, 2018 - frontiersin.org
Introduction Vitamin D deficiency is an important public health problem worldwide. Vitamin D
deficiency confers a significant risk for both skeletal and non-skeletal disorders and a …

Nongenomic activities of vitamin D

MA Żmijewski - Nutrients, 2022 - mdpi.com
Vitamin D shows a variety of pleiotropic activities which cannot be fully explained by the
stimulation of classic pathway-and vitamin D receptor (VDR)-dependent transcriptional …

Vitamin D receptor (s): In the nucleus but also at membranes?

MA Zmijewski, C Carlberg - Experimental Dermatology, 2020 - Wiley Online Library
The genomic actions of the vitamin D are mediated via its biologically most potent metabolite
1α, 25‐dihydroxyvitamin D3 (1, 25 (OH) 2D3) and the transcription factor vitamin D receptor …

Serum 25-hydroxyvitamin D and cancer risk: a systematic review of Mendelian randomization studies

T Lawler, S Warren Andersen - Nutrients, 2023 - mdpi.com
Epidemiological studies suggest that higher serum 25-hydroxyvitamin D is associated with
lower risk for several cancers, including breast, prostate, colorectal, and lung cancers. To …

Drug delivery systems for vitamin D supplementation and therapy

E Glowka, J Stasiak, J Lulek - Pharmaceutics, 2019 - mdpi.com
Vitamin D (VD) is a fat-soluble prohormone well known for its role in regulating calcium and
phosphate metabolism. It has been clinically used for many years to prevent rickets in …

[HTML][HTML] Vitamin D baseline levels at diagnosis of breast cancer: A systematic review and meta-analysis

IA Voutsadakis - Hematology/oncology and stem cell therapy, 2021 - Elsevier
Background Vitamin D is a steroid hormone that exerts its actions through ligation of the
vitamin D receptor (VDR), a transcription factor of the nuclear receptor family. VDR has not …

Oral photoprotection: effective agents and potential candidates

C Parrado, N Philips, Y Gilaberte, A Juarranz… - Frontiers in …, 2018 - frontiersin.org
Electromagnetic radiation in the ultraviolet, visible, and infrared ranges produces biologic
effects in humans. Where some of these effects are beneficial, others are harmful to the skin …