Quinquennial review of progress in degradation studies and impurity profiling: an instrumental perspective statistics

M Shelke, SS Deshpande, S Sharma - Critical reviews in analytical …, 2020 - Taylor & Francis
Degradation studies of drug give insightful information about the intrinsic stability of the
molecule, the possible degradents formed during shelf life and thus, aid in the subsequent …

Dissimilarity of different cephalosporins on volatile fatty acids production and antibiotic resistance genes fates during sludge fermentation and underlying mechanisms

J Luo, Y Li, W Huang, F Wang, S Fang, X Cheng… - Chinese Chemical …, 2023 - Elsevier
The distinct influences of cephalosporins (CEPs, ie, cefamandole nafate and cefpirome
sulfate) affiliated to different generations on the volatile fatty acids (VFAs) production and …

Adsorption equilibrium, kinetics, and thermodynamic studies of cefpirome sulfate by using macroporous resin

F Xue, F Wang, S Chen, S Ju… - Journal of Chemical & …, 2017 - ACS Publications
The adsorption thermodynamics, kinetics, and isotherm parameters of cefpirome sulfate in
aqueous solution on macroporous resin (XAD-16) were studied. Using static equilibrium …

Separation and characterization of impurities and isomers in cefpirome sulfate by liquid chromatography/tandem mass spectrometry and a summary of the …

X Ren, J Zhou, J Wang - Rapid Communications in Mass …, 2021 - Wiley Online Library
Rationale Although the identification of degradation products of cefpirome sulfate has been
reported, there has been no report concerning the impurities in bulk samples of this …

Dose optimization of cefpirome based on population pharmacokinetics and target attainment during extracorporeal membrane oxygenation

S Kang, JY Jang, J Hahn, D Kim, JY Lee… - Antimicrobial agents …, 2020 - Am Soc Microbiol
To obtain the optimal dosage regimen in patients receiving extracorporeal membrane
oxygenation (ECMO), we developed a population pharmacokinetics model for cefpirome …

[HTML][HTML] Radiolytic studies of cefozopran hydrochloride in the solid state

P Zalewski, R Skibiński… - Electronic Journal of …, 2017 - Elsevier
Background The radiation sterilization is one of the best methods for sterilizing vulnerable
degradation drugs like cefozopran hydrochloride. Results Chemical stability of …

Ratio manipulating spectrophotometry versus chemometry as stability indicating methods for cefquinome sulfate determination

AM Yehia, RM Arafa, SS Abbas, SM Amer - Spectrochimica Acta Part A …, 2016 - Elsevier
Spectral resolution of cefquinome sulfate (CFQ) in the presence of its degradation products
was studied. Three selective, accurate and rapid spectrophotometric methods were …

Characterization of three main degradation products from novel oral anticoagulant rivaroxaban under stress conditions by UPLC-Q-TOF-MS/MS

NR Wingert, NO dos Santos, MAG Nunes… - … of pharmaceutical and …, 2016 - Elsevier
Drugs of long-term use may cause the accumulation of chemical compounds in human
body. Therefore, the evaluation and structure characterization of synthesis and degradation …

Investigation on the interaction of cefpirome sulfate with lysozyme by fluorescence quenching spectroscopy and synchronous fluorescence spectroscopy

R Han, B Liu, G Li, Q Zhang - Luminescence, 2016 - Wiley Online Library
The reaction mechanism of cefpirome sulfate with lysozyme at different temperatures (298,
310 and 318 K) was investigated using fluorescence quenching and synchronous …

Stability studies of cefoselis sulfate in the solid state

P Zalewski, R Skibiński, A Talaczyńska… - … of Pharmaceutical and …, 2015 - Elsevier
The process of degradation was studied by using an HPLC–DAD method. Two degradation
products were identified with a hybrid ESI-Q-TOF mass spectrometer. The influence of …