Methicillin-resistant Staphylococcus aureus (MRSA) infection is still a major global
healthcare problem. Of concern is S. aureus bacteremia, which exhibits high rates of …

Importance Several management strategies may improve outcomes in patients
withStaphylococcus aureusbacteremia. Objectives To review evidence of management …

Vancomycin is a glycopeptide antibiotic that is active against Gram-positive bacteria,
including methicillin-resistant Staphylococcus aureus. Nephrotoxicity, which is usually …

Background Recent guidelines have recommended vancomycin trough levels of 15–20
mg/L for treatment of serious infections caused by methicillin-resistant Staphylococcus …

Background Outcomes data for the efficacy of interventions designed to decrease the time to
initial target vancomycin troughs are sparse. Objective A vancomycin therapeutic drug …

The purpose of this study was to compare the clinical efficacy and safety of vancomycin to
those of teicoplanin for the treatment of adult patients with health care-associated methicillin …

Importance Staphylococcus aureusis the leading cause of death due to bacterial
bloodstream infection. Female sex has been identified as a risk factor for mortality inS …

Background Clinical risk factors for nephrotoxicity in Staphylococcus aureus bacteraemia
remain largely undetermined, despite its common occurrence and clinical significance. In an …

Background The purported value of empirical therapy to cover methicillin-resistant
Staphylococcus aureus (MRSA) has been debated for decades. The purpose of this study …

Background Previous studies have established a correlation between vancomycin troughs
and nephrotoxicity. However, data are currently lacking regarding the effect of guideline …