Many soft tissues are naturally made of a matrix and fibres that present some privileged
directions. They are known to support large reversible deformations. The mechanical …

Biomechanical factors play fundamental roles in the natural history of abdominal aortic
aneurysms (AAAs) and their responses to treatment. Advances during the past two decades …

The established method of polarized microscopy in combination with a universal stage is
used to determine the layer-specific distributed collagen fibre orientations in 11 human non …

The recruitment of patients for rare or complex cardiovascular diseases is a bottleneck for
clinical trials and digital twins of the human heart have recently been proposed as a viable …

There has been a growing awareness over the past decade that stiffening of the aorta, and
its attendant effects on hemodynamics, is both an indicator and initiator of diverse …

The patient-specific biomechanical analysis of the aorta requires the quantification of the in
vivo mechanical properties of individual patients. Current inverse approaches have …

Transcatheter aortic valve implantation (TAVI) enables treatment of aortic stenosis with no
need for open heart surgery. According to current guidelines, only patients considered at …

Among the three layers of the aortic wall, the media is primarily responsible for its
mechanical properties, but the adventitia prevents the aorta from overstretching and …

In a previous study we were able to accurately fit experimental data on arterial tissues at
supra-physiological loads using a material model that accounts for softening/damage only in …

Elastic arteries are significantly prestretched in an axial direction. This property minimises
axial deformations during pressure cycle. Ageing-induced changes in arterial biomechanics …