The relationship between molecular content of mesenchymal stem cells derived exosomes and their potentials: opening the way for exosomes based therapeutics

D Jafari, S Malih, SS Eslami, R Jafari, L Darzi, P Tarighi… - Biochimie, 2019 - Elsevier
At least, more than half of our understanding of extracellular vesicles owes to the studies
conducted over the past few years. When it became clear that the exosomes have various …

Genistein exerts a cell-protective effect via nrf2/ho-1//pi3k signaling in ab25-35-induced alzheimer's disease models in vitro

S Yi, S Chen, J Xiang, J Tan, K Huang… - Folia histochemica …, 2021 - journals.viamedica.pl
Introduction. Alzheimer's disease (AD), a very common neurodegenerative disorder, is
mainly characterized by the deposition of b-amyloid protein (Ab) and extensive neuronal cell …

Evaluation of vacuum washing in the removal of SDS from decellularized bovine pericardium: method and device description

M Alizadeh, L Rezakhani, M Soleimannejad, E Sharifi… - Heliyon, 2019 - cell.com
Aims The aim of this study was to present a new method for removing Sodium dodecyl
sulfate (SDS) detergent from decellularized bovine pericardium using vacuum. Materials …

Therapeutic effects of melatonin-treated bone marrow mesenchymal stem cells (BMSC) in a rat model of Alzheimer's disease

M Ramezani, A Komaki, N Hashemi-Firouzi… - Journal of Chemical …, 2020 - Elsevier
The therapy based on mesenchymal stem cells (MSCs) has received growing attraction for
Alzheimer's disease (AD). However, a great challenge in this regard is the low survival rate …

Neuroprotective effects of Coptis chinensis Franch polysaccharide on amyloid-beta (Aβ)-induced toxicity in a transgenic Caenorhabditis elegans model of Alzheimer's …

Y Li, S Guan, C Liu, X Chen, Y Zhu, Y Xie… - International journal of …, 2018 - Elsevier
This study aims to investigate the neuroprotective effects of Coptis chinensis Franch
polysaccharide (CCP) on Aβ 1–42 transgenic CL4176 Caenorhabditis elegans, as well as …

[HTML][HTML] Comparison of the melatonin preconditioning efficacy between bone marrow and adipose-derived mesenchymal stem cells

A Rafat, AM Roushandeh, A Alizadeh… - Cell Journal …, 2019 - ncbi.nlm.nih.gov
Objective Mesenchymal stem cells (MSC) from various sources have the potentials to
positively affect regenerative medicine. Furthermore, pre-conditioning strategies with …

Preconditioning adipose-derived mesenchymal stem cells with dimethyl fumarate promotes their therapeutic efficacy in the brain tissues of rats with Alzheimer's …

H Babaei, A Kheirollah, M Ranjbaran… - Biochemical and …, 2023 - Elsevier
Aim Transplantation of mesenchymal stem cell (MSC) has been suggested to be a
promising method for treating neurodegenerative conditions, including Alzheimer's disease …

Infusion of hESC derived immunity‐and‐matrix regulatory cells improves cognitive ability in early‐stage AD mice

J Liu, Z Hou, J Wu, K Liu, D Li, T Gao, W Liu… - Cell …, 2021 - Wiley Online Library
Objectives In this study, we administered immunity‐and‐matrix regulatory cells (IMRCs) via
tail vein (IV) and intracerebroventricular (ICV) injection to 3‐month‐old 5× FAD transgenic …

Fasudil in combination with bone marrow stromal cells (BMSCs) attenuates Alzheimer's disease-related changes through the regulation of the peripheral immune …

J Yu, Y Yan, Q Gu, G Kumar, H Yu, Y Zhao… - Frontiers in Aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease. Its
mechanism is still not clear. Majority of research focused on the central nervous system …

[HTML][HTML] Dental Pulp Stem Cells Transplantation Improves Passive Avoidance Memory and Neuroinflammation in Trimethyltin-Induced Alzheimer's Disease Rat Model

S Malekzadeh, MA Edalatmanesh… - Galen Medical …, 2021 - journals.salviapub.com
Background: According to the increasing incidence of Alzheimer's disease (AD), this study
aimed to investigate the effect of dental pulp stem cells (DPSCs) transplantation on passive …