A central aspect of nervous system development and function is the post-transcriptional
regulation of mRNA fate, which implies time-and site-dependent translation, in response to …

Stress granules (SGs) constitute a signaling hub that plays a critical role in type I interferon
responses. Here, we report that growth arrest and DNA damage-inducible beta (Gadd45β) …

Genotoxic stress leads to DNA damage which can be detrimental to the cell. A well‐
orchestrated cellular response is mounted to manage and repair the genotoxic stress …

Dysregulation of G9a, a histone-lysine N-methyltransferase, has been observed in
Alzheimer's disease and has been correlated with increased levels of chronic inflammation …

Background The growth arrest and DNA damage-inducible 45 (Gadd45) gene has been
implicated in various central nervous system (CNS) functions, both normal and pathological …

Gadd45 genes have been implicated in survival mechanisms, including apoptosis,
autophagy, cell cycle arrest, and DNA repair, which are processes related to aging and life …

Neurons respond rapidly to extracellular stimuli by activating signaling pathways that
modulate the function of already synthetized proteins. Alternatively, signal transduction to …

After many decades, during which most molecular studies on the regulation of gene
expression focused on transcriptional events, it was realized that post-transcriptional control …

Although light emitting diodes (LEDs) are widely used in our daily lives, there is little
research regarding LED light's possible effects on biological functions. We used a zebrafish …

Background Several studies indicate general anesthetics can produce lasting effects on
cognitive function. The commonly utilized anesthetic agent Sevoflurane has been implicated …