Inflammation‐related mechanisms in chronic kidney disease prediction, progression, and outcome
S Mihai, E Codrici, ID Popescu… - Journal of …, 2018 - Wiley Online Library
Persistent, low‐grade inflammation is now considered a hallmark feature of chronic kidney
disease (CKD), being involved in the development of all‐cause mortality of these patients …
disease (CKD), being involved in the development of all‐cause mortality of these patients …
Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy
The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …
Extracellular matrix in kidney fibrosis: more than just a scaffold
Kidney fibrosis is the common histological end-point of progressive, chronic kidney diseases
(CKDs) regardless of the underlying etiology. The hallmark of renal fibrosis, similar to all …
(CKDs) regardless of the underlying etiology. The hallmark of renal fibrosis, similar to all …
[HTML][HTML] Diagnosis of diabetic kidney disease: state of the art and future perspective
Approximately 20% to 40% of patients with type 1 or type 2 diabetes mellitus develop
diabetic kidney disease. This is a clinical syndrome characterized by persistent albuminuria …
diabetic kidney disease. This is a clinical syndrome characterized by persistent albuminuria …
Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective …
N Tofte, M Lindhardt, K Adamova… - The lancet Diabetes & …, 2020 - thelancet.com
Background Microalbuminuria is an early sign of kidney disease in people with diabetes and
indicates increased risk of cardiovascular disease. We tested whether a urinary proteomic …
indicates increased risk of cardiovascular disease. We tested whether a urinary proteomic …
Novel biomarkers in the diagnosis of chronic kidney disease and the prediction of its outcome
J Rysz, A Gluba-Brzózka, B Franczyk… - International journal of …, 2017 - mdpi.com
In its early stages, symptoms of chronic kidney disease (CKD) are usually not apparent.
Significant reduction of the kidney function is the first obvious sign of disease. If diagnosed …
Significant reduction of the kidney function is the first obvious sign of disease. If diagnosed …
Proteomics and metabolomics in kidney disease, including insights into etiology, treatment, and prevention
RF Dubin, EP Rhee - Clinical Journal of the American Society of …, 2020 - journals.lww.com
In this review of the application of proteomics and metabolomics to kidney disease research,
we review key concepts, highlight illustrative examples, and outline future directions. The …
we review key concepts, highlight illustrative examples, and outline future directions. The …
Peptidomics and proteomics based on CE‐MS as a robust tool in clinical application: The past, the present, and the future
Capillary electrophoresis combined with mass spectrometry (CE‐MS) has been used for
several years for the investigation of proteins and peptides as biomarkers for diagnosis and …
several years for the investigation of proteins and peptides as biomarkers for diagnosis and …
[HTML][HTML] 2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications
N Gonzalez, I Prieto, L del Puerto-Nevado… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Worldwide deaths from diabetes mellitus (DM) and colorectal cancer increased by 90% and
57%, respectively, over the past 20 years. The risk of colorectal cancer was estimated to be …
57%, respectively, over the past 20 years. The risk of colorectal cancer was estimated to be …
A urinary proteome-based classifier for the early detection of decline in glomerular filtration
C Pontillo, L Jacobs, JA Staessen… - Nephrology Dialysis …, 2017 - academic.oup.com
Background. Chronic kidney disease (CKD) progression is currently assessed by a decline
in estimated glomerular filtration rate (eGFR) and/or an increase in urinary albumin excretion …
in estimated glomerular filtration rate (eGFR) and/or an increase in urinary albumin excretion …