Immunotherapy revolutionizing brain metastatic cancer treatment: personalized strategies for transformative outcomes

T Li, S Sun, Y Li, Y Zhang, L Wei - Frontiers in Immunology, 2024 - frontiersin.org
Brain metastatic cancer poses a significant clinical challenge, with limited treatment options
and poor prognosis for patients. In recent years, immunotherapy has emerged as a …

Microengineered in vitro CAR T cell screens and assays

J Kim, SN Thomas - Cell Systems, 2024 - cell.com
Established and emergent microengineered in vitro systems enable the evaluation of
chimeric antigen receptor (CAR) T cell product purity, avidity, and functionality. Here, we …

RNA aggregates harness the danger response for potent cancer immunotherapy

HR Mendez-Gomez, A DeVries, P Castillo… - Cell, 2024 - cell.com
Cancer immunotherapy remains limited by poor antigenicity and a regulatory tumor
microenvironment (TME). Here, we create" onion-like" multi-lamellar RNA lipid particle …

Comparison of structural characteristics and anti-tumor activity of two alkali extracted peach gum arabinogalactan

K Dai, W Ding, Z Li, C Liu, H Ji, A Liu - International Journal of Biological …, 2024 - Elsevier
Two polysaccharides, PGP-90 and PGP-100 (molecular weights of 7.59× 10 2 kDa and
10.48× 10 2 kDa, respectively), were isolated from Peach gum using alkaline electrolyte …

Applications of Intravital Imaging in Cancer Immunotherapy

D Deng, T Hao, L Lu, M Yang, Z Zeng, JF Lovell, Y Liu… - Bioengineering, 2024 - mdpi.com
Currently, immunotherapy is one of the most effective treatment strategies for cancer.
However, the efficacy of any specific anti-tumor immunotherapy can vary based on the …