Introduction Evidence-based recommendations are needed to guide the acute management
of the bleeding trauma patient. When these recommendations are implemented patient …

Recent progress has been made in the identification and implementation of best transfusion
practices on the basis of evidence-based clinical trials, published clinical practice …

Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Background The resuscitation of severely injured bleeding patients has evolved into a multi-
modal strategy termed damage control resuscitation (DCR). This guideline evaluates …

Background: Massive transfusion (MT) occurs in about 3% of civilian and 8% of military
trauma patients. Although many centers have implemented MT protocols, most do not have …

Objective: To determine whether implementation of damage control resuscitation (DCR) in
patients undergoing damage control laparotomy (DCL) translates into improved survival …

Background: Recognition of trauma-induced coagulopathy by conventional coagulation
testing (CCT) is limited by their slow results, incomplete characterization, and their poor …

Objective. Earlier use of plasma and red blood cells (RBCs) has been associated with
improved survival in trauma patients with substantial hemorrhage. We hypothesized that …

Background: Several studies have described predictive models to identify trauma patients
who require massive transfusion (MT). Early identification of lethal exsanguination may …

Before 2005, reported mortalities for patients receiving a massive transfusion (MT) were
55% to 65%. 1, 2 Mortality remained at this level through 2007, dropping to 45% to 50% with …