Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Modulation of immune responses by particle size and shape

MV Baranov, M Kumar, S Sacanna… - Frontiers in …, 2021 - frontiersin.org
The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

SM Man, R Karki, TD Kanneganti - Immunological reviews, 2017 - Wiley Online Library
Cell death is a fundamental biological phenomenon that is essential for the survival and
development of an organism. Emerging evidence also indicates that cell death contributes to …

An overlooked and underrated endemic mycosis—Talaromycosis and the pathogenic fungus Talaromyces marneffei

F Wang, RH Han, S Chen - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Talaromycosis is an invasive mycosis endemic in tropical and subtropical Asia and is
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …

Candida albicans-Biology, molecular characterization, pathogenicity, and advances in diagnosis and control–An update

M Dadar, R Tiwari, K Karthik, S Chakraborty… - Microbial …, 2018 - Elsevier
Candida albicans is an emerging multidrug-resistant fungal pathogen representing an
important source of invasive disease in humans and generating high healthcare costs …

The contribution of the human oral microbiome to oral disease: a review

AG Morrison, S Sarkar, S Umar, STM Lee, SM Thomas - Microorganisms, 2023 - mdpi.com
The oral microbiome is an emerging field that has been a topic of discussion since the
development of next generation sequencing and the implementation of the human …

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

L Kasper, A König, PA Koenig, MS Gresnigt… - Nature …, 2018 - nature.com
Clearance of invading microbes requires phagocytes of the innate immune system.
However, successful pathogens have evolved sophisticated strategies to evade immune …

Candida and Candidiasis—Opportunism Versus Pathogenicity: A Review of the Virulence Traits

CN Ciurea, IB Kosovski, AD Mare, F Toma… - Microorganisms, 2020 - mdpi.com
One of the most important questions in microbiology nowadays, is how apparently harmless,
commensal yeasts like Candida spp. can cause a rising number of infections. The …

Cytosolic recognition of microbes and pathogens: inflammasomes in action

JA Hayward, A Mathur, C Ngo… - … and Molecular Biology …, 2018 - Am Soc Microbiol
Infection is a dynamic biological process underpinned by a complex interplay between the
pathogen and the host. Microbes from all domains of life, including bacteria, viruses, fungi …