Advances in structure elucidation of small molecules using mass spectrometry
The structural elucidation of small molecules using mass spectrometry plays an important
role in modern life sciences and bioanalytical approaches. This review covers different soft …
role in modern life sciences and bioanalytical approaches. This review covers different soft …
Orbitrap mass spectrometry: instrumentation, ion motion and applications
Since its introduction, the orbitrap has proven to be a robust mass analyzer that can routinely
deliver high resolving power and mass accuracy. Unlike conventional ion traps such as the …
deliver high resolving power and mass accuracy. Unlike conventional ion traps such as the …
Performance characteristics of electron transfer dissociation mass spectrometry
We performed a large scale study of electron transfer dissociation (ETD) performance, as
compared with ion trap collision-activated dissociation (CAD), for peptides ranging from∼ …
compared with ion trap collision-activated dissociation (CAD), for peptides ranging from∼ …
Peptide radicals and cation radicals in the gas phase
For about three decades, the chemistry of cation radicals derived from organic molecules
had received a major impetus from mass spectrometry. This was because cation radicals …
had received a major impetus from mass spectrometry. This was because cation radicals …
Application of electron transfer dissociation (ETD) for the analysis of posttranslational modifications
J Wiesner, T Premsler, A Sickmann - Proteomics, 2008 - Wiley Online Library
Despite major advantages in the field of proteomics, the analysis of PTMs still poses a major
challenge; thus far, preventing insights into the role and regulation of protein networks …
challenge; thus far, preventing insights into the role and regulation of protein networks …
Electron transfer dissociation mass spectrometry in proteomics
Mass spectrometry has rapidly evolved to become the platform of choice for proteomic
analysis. While CID remains the major fragmentation method for peptide sequencing …
analysis. While CID remains the major fragmentation method for peptide sequencing …
Surface desorption atmospheric pressure chemical ionization mass spectrometry for direct ambient sample analysis without toxic chemical contamination
H Chen, J Zheng, X Zhang, M Luo… - Journal of mass …, 2007 - Wiley Online Library
Ambient mass spectrometry, pioneered with desorption electrospray ionization (DESI)
technique, is of increasing interest in recent years. In this study, a corona discharge …
technique, is of increasing interest in recent years. In this study, a corona discharge …
Gas-phase ion/ion reactions involving tris-phenanthroline alkaline earth metal complexes as charge inversion reagents for the identification of fatty acids
CE Randolph, DJ Foreman, SK Betancourt… - Analytical …, 2018 - ACS Publications
Fatty acids (FA) play vital biological roles as energy sources, signaling molecules and key
building blocks of complex lipids in cell membranes. Modifications to FA structure and …
building blocks of complex lipids in cell membranes. Modifications to FA structure and …
Implementation of electron-transfer dissociation on a hybrid linear ion trap− orbitrap mass spectrometer
We describe the adaptation of a hybrid quadrupole linear ion trap− orbitrap mass
spectrometer to accommodate electron-transfer ion/ion reactions (ETD) for peptide and …
spectrometer to accommodate electron-transfer ion/ion reactions (ETD) for peptide and …
Collisions or electrons? Protein sequence analysis in the 21st century
JJ Coon - 2009 - ACS Publications
Five years ago, researchers discovered that electron-capture-dissociation-like fragmentation
could occur when peptide cations were reacted with radical anions. This technique, electron …
could occur when peptide cations were reacted with radical anions. This technique, electron …