Role of LDH in tumor glycolysis: regulation of LDHA by small molecules for cancer therapeutics

D Sharma, M Singh, R Rani - Seminars in cancer biology, 2022 - Elsevier
Lactate dehydrogenase (LDH) is one of the crucial enzymes in aerobic glycolysis, catalyzing
the last step of glycolysis, ie. the conversion of pyruvate to lactate. Most cancer cells are …

[HTML][HTML] Exploring the plant-derived bioactive substances as antidiabetic agent: an extensive review

MM Rahman, PS Dhar, F Anika, L Ahmed… - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus (DM) is a metabolic syndrome. Diabetes has become more common in
recent years. Chemically generated drugs are used to lessen the effects of DM and its …

GC–MS analysis of phytoconstituents from Amomum nilgiricum and molecular docking interactions of bioactive serverogenin acetate with target proteins

N Konappa, AC Udayashankar, S Krishnamurthy… - Scientific reports, 2020 - nature.com
Amomum nilgiricum is one of the plant species reported from Western Ghats of India,
belonging to the family Zingiberaceae, with ethno-botanical values, and is well-known for …

Pharmacokinetics and drug-likeness of antidiabetic flavonoids: Molecular docking and DFT study

M Bitew, T Desalegn, TB Demissie, A Belayneh… - Plos one, 2021 - journals.plos.org
Computer aided toxicity and pharmacokinetic prediction studies attracted the attention of
pharmaceutical industries as an alternative means to predict potential drug candidates. In …

Antioxidant effects and mechanisms of medicinal plants and their bioactive compounds for the prevention and treatment of type 2 diabetes: an updated review

JO Unuofin, SL Lebelo - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …

Probiotics: versatile bioactive components in promoting human health

J Sharifi-Rad, CF Rodrigues, Z Stojanović-Radić… - Medicina, 2020 - mdpi.com
The positive impact of probiotic strains on human health has become more evident than ever
before. Often delivered through food, dietary products, supplements, and drugs, different …

Pharmacologically active phytomolecules isolated from traditional antidiabetic plants and their therapeutic role for the management of diabetes mellitus

P Ansari, S Akther, JMA Hannan, V Seidel, NJ Nujat… - Molecules, 2022 - mdpi.com
Diabetes mellitus is a chronic complication that affects people of all ages. The increased
prevalence of diabetes worldwide has led to the development of several synthetic drugs to …

A Comprehensive Review on Chemical Profile and Pharmacological Activities of Ocimum basilicum

K Dhama, K Sharun, MB Gugjoo, R Tiwari… - Food Reviews …, 2023 - Taylor & Francis
Herbs and plant metabolites/extracts are gaining wide attention owing to their multiple
beneficial health effects, medicinal values, and nutraceutical properties, particularly in the …

Moroccan antidiabetic medicinal plants: Ethnobotanical studies, phytochemical bioactive compounds, preclinical investigations, toxicological validations and clinical …

A Bouyahya, N El Omari, N Elmenyiy… - Trends in Food Science …, 2021 - Elsevier
Background Moroccan flora is rich with medicinal plants that are widely used in traditional
medicine for the treatment of various diseases including diabetes. These plants possess …

[HTML][HTML] Phytochemicals from edible flowers: Opening a new arena for healthy lifestyle

P Kumari, B Bhargava - Journal of Functional Foods, 2021 - Elsevier
Demand for more attractive and high quality food is growing every day. The increasing
interest in functional foods and nutraceuticals has exaggerated exploration into new foods …