Application of citicoline in neurological disorders: a systematic review

P Jasielski, F Piędel, M Piwek, A Rocka, V Petit… - Nutrients, 2020 - mdpi.com
Citicoline is a chemical compound involved in the synthesis of cell membranes. It also has
other, not yet explained functions. Research on the use of citicoline is conducted in …

[PDF][PDF] Citicoline: pharmacological and clinical review, 2010 update

JJ Secades - Rev Neurol, 2011 - researchgate.net
This review is based on the previous one published in 2010–Secades JJ. Citicoline:
pharmacological and clinical review, 2010 update. Rev Neurol 2011; 52 (Suppl 2): S1-62 …

Sophisticated polycaprolactone/gelatin nanofibrous nerve guided conduit containing platelet-rich plasma and citicoline for peripheral nerve regeneration: in vitro and …

H Samadian, A Ehterami, A Sarrafzadeh… - International journal of …, 2020 - Elsevier
Peripheral nerve injury (PNI) is a devastating condition that may result in loss of sensory
function, motor function, or both. In the present study, we construct an electrospun nerve …

Synthesis and characterization of alginate and sterculia gum based hydrogel for brain drug delivery applications

B Singh, A Kumar - International journal of biological macromolecules, 2020 - Elsevier
The present work deals with the design of the alginate, sterculia gum polysaccharide and
PVP based hydrogel for brain drug delivery applications. The release dynamics of citicoline …

The influence of drugs on peripheral nerve regeneration

O Bota, L Fodor - Drug metabolism reviews, 2019 - Taylor & Francis
Currently, there are no established adjuvant drugs for the acceleration of peripheral nerve
regeneration. In this paper, we reviewed the literature from the last 10 years and described …

Gamma radiation formation of sterculia gum-alginate-carbopol hydrogel dressing by grafting method for use in brain drug delivery

B Singh, A Kumar - Chemical Physics Letters, 2021 - Elsevier
As the brain injury causes persistent neurological disorders that lead to the loss of neuron
functions. The blood–brain-barrier limits the bioavailability of drugs required in therapeutic …

[HTML][HTML] The impact of supplements on recovery after peripheral nerve injury: a review of the literature

Y Abushukur, R Knackstedt - Cureus, 2022 - ncbi.nlm.nih.gov
Peripheral nerve injury (PNI) can result from trauma, surgical resection, iatrogenic injury,
and/or local anesthetic toxicity. Damage to peripheral nerves may result in debilitating …

Intraperitoneal administration of CDP-choline or a combination of cytidine plus choline improves nerve regeneration and functional recovery in a rat model of sciatic …

B Caner, MI Kafa, A Bekar, MA Kurt, N Karli… - Neurological …, 2012 - Taylor & Francis
Abstract Objective: Topical cytidine-5′-diphosphocholine (CDP-choline) improves
functional recovery and promotes nerve regeneration in sciatic nerve injury in rats. The aims …

Investigation of the dose-dependency of citicoline effects on nerve regeneration and functional recovery in a rat model of sciatic nerve injury

T Kaplan, IM Kafa, M Cansev, A Bekar, N Karlı… - 2014 - acikerisim.uludag.edu.tr
AIM: The aim of this study was to investigate the dose dependence of citicoline's previously-
reported effects on recovery of peripheral nerve injury. MATERIAL and METHODS: Right …

Cytidine 5′-diphosphocholine administration prevents peripheral neuropathic pain after sciatic nerve crush injury in rats

DR Emril, S Wibowo, L Meliala… - Journal of pain …, 2016 - Taylor & Francis
Background Cytidine 5′-diphosphocholine (citicoline) has been shown to have beneficial
effects in central nervous system injury as well as in motoric functional recovery after …