Background. Nowadays, the immunomodulatory properties of plants have been studied
extensively with greater interest due to increasing awareness and combating the severity of …

Accurate and timely diagnosis of primary immunodeficiencies (PID) is an ongoing effort.
Individuals with PID can be severely impacted by their disease and many experience …

Background Inborn errors of immunity (IEI) are rare diseases, which makes diagnosis a
challenge. A better description of the initial presenting manifestations should improve …

Background Primary immunodeficiencies (PI), which include more than 450 single-gene
inborn errors of immunity and may affect up to 1% of the population, are genetic disorders …

Background Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected
individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the …

Background Inborn errors of immunity (IEIs) are a heterogeneous group of genetic defects of
immunity, which cause high rates of morbidity and mortality mainly among children due to …

Primary immunodeficiencies (PIDs) are heterogeneous, rare disorders that increase
susceptibility to infection and/or immune dysregulation. Individuals with certain PIDs are at …

A global gold standard framework for primary immunodeficiency (PID) care, structured
around six principles, was published in 2014. To measure the implementation status of …

Complement not only plays a key role in host microbial defense but also modulates the
adaptive immune response through modification of T-and B-cell reactivity. Moreover, a …

Inborn errors of immunity represent a rapidly expanding group of genetic disorders of the
immune system. Significant advances have been made in recent years in diagnosis …