Novel phytonutrient contributors to antioxidant protection against cardiovascular disease

G Riccioni, L Speranza, M Pesce, S Cusenza… - Nutrition, 2012 - Elsevier
The associations linking endothelial inflammation, endothelial oxidative stress, and
atherogenesis and the potential for dietary phytonutrients to decrease the impact of these …

[HTML][HTML] Function and treatment strategies of β-hydroxybutyrate in aging

Y Xiang, QQ Wang, XQ Lan, HJ Zhang… - Smart Materials in …, 2023 - Elsevier
Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy
source for life activities, and signals for environmental adaptation. Ketone bodies are …

Mitochondrial dysfunction contributes to hypertensive target organ damage: lessons from an animal model of human disease

S Rubattu, R Stanzione, M Volpe - Oxidative medicine and …, 2016 - Wiley Online Library
Mechanisms underlying hypertensive target organ damage (TOD) are not completely
understood. The pathophysiological role of mitochondrial oxidative stress, resulting from …

Green Tea Polyphenols Ameliorate the Early Renal Damage Induced by a High‐Fat Diet via Ketogenesis/SIRT3 Pathway

W Yi, X Xie, M Du, Y Bu, N Wu, H Yang… - Oxidative medicine …, 2017 - Wiley Online Library
Scope. Several reports in the literature have suggested the renoprotective effects of ketone
bodies and green tea polyphenols (GTPs). Our previous study found that GTP consumption …

Clofibrate, a peroxisome proliferator–activated receptor-alpha (PPARα) agonist, and its molecular mechanisms of action against sodium fluoride–induced toxicity

AA Oyagbemi, OA Adejumobi, TA Jarikre… - … Trace Element Research, 2022 - Springer
Sodium fluoride (NaF) is one of the neglected environmental pollutants. It is ubiquitously
found in the soil, water, and environment. Interestingly, fluoride has been extensively utilized …

Insulin resistance, oxidative stress and cardiovascular complications: role of sirtuins

PK Bagul, SK Banerjee - Current pharmaceutical design, 2013 - ingentaconnect.com
Cardiovascular disease (CVD) is one of the major lifestyle associated disorders and leading
causes of death worldwide. The incidence of CVD in diabetic patients has increased up to 3 …

Fenofibrate attenuates cardiac and renal alterations in young salt-loaded spontaneously hypertensive stroke-prone rats through mitochondrial protection

L Castiglioni, A Pignieri, M Fiasche… - Journal of …, 2018 - journals.lww.com
Objectives: The simultaneous presence of cardiac and renal diseases is a pathological
condition that leads to increased morbidity and mortality. Several lines of evidence have …

1, 25 (OH) 2D3 alleviates oxidative stress and inflammation through up-regulating HMGCS2 in DSS-induced colitis

HQ Wang, MX Zhao, SC Hong, X He, L Tao… - International …, 2023 - Elsevier
Background Previous study found that supplements with active vitamin D3 alleviated
experimental colitis. The objective of this study was to investigate the possible role of 3 …

Effects of high fat feeding on adipose tissue gene expression in diabetic Goto-Kakizaki rats

B Xue, J Nie, X Wang, DC DuBois… - Gene Regulation …, 2015 - journals.sagepub.com
Development and progression of type 2 diabetes is a complex interaction between genetics
and environmental influences. High dietary fat is one environmental factor that is conducive …

E4orf1, an Adeno-viral protein, attenuates renal lipid accumulation in high fat fed mice: A novel approach to reduce a key risk factor for chronic kidney disease

R Afruza, M Akheruzzaman, NV Dhurandhar, V Hegde - Heliyon, 2020 - cell.com
Obesity and hyperlipidemia are independent risk factors of chronic kidney disease (CKD). In
mice, diet induced obesity accelerates lipogenesis, lipid accumulation, and injury in kidneys …