To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …

Serine/glycine biosynthesis and one-carbon metabolism are crucial in sustaining cancer cell
survival and rapid proliferation, and of high clinical relevance. Excessive activation of …

Nuclear factor-kappaB (NF-ĸB) plays a crucial role in both innate and adaptive immune
systems, significantly influencing various physiological processes such as cell proliferation …

Prostate cancer (PCa) is the second most diagnosed cancer in men worldwide. For its
screening, serum prostate specific antigen (PSA) test has been largely performed over the …

The serine-glycine-one-carbon (SGOC) metabolic pathway is critical for DNA methylation,
histone methylation, and redox homeostasis, in addition to protein, lipid, and nucleotide …

Abstract Background Methyltransferase 3 (METTL3)‐mediated N6‐methyladenosine (m6A)
RNA modification has been demonstrated to be a potential factor in promoting gastric cancer …

Short-chain fatty acids (SCFAs) exhibit anticancer activity in cellular and animal models of
colon cancer. Acetate, propionate, and butyrate are the three major SCFAs produced from …

Aims: This study was launched to identify the SHMT2 associated Human Cancer subtypes.
Background: Cancer is the 2nd leading cause of death worldwide. Previous reports revealed …

Background Colorectal cancer (CRC) is prevalent worldwide and is often challenged by
treatment failure and recurrence due to resistance to radiotherapy. Here, we aimed to …

Doxorubicin, a member of the anthracycline family, is a widely prescribed anticancer
chemotherapy drug. Unfortunately, cumulative doses of doxorubicin can cause …