Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

[HTML][HTML] Implications of hydrogen sulfide in colorectal cancer: Mechanistic insights and diagnostic and therapeutic strategies

H Lin, Y Yu, L Zhu, N Lai, L Zhang, Y Guo, X Lin… - Redox Biology, 2023 - Elsevier
Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

A hydrogen sulphide-responsive and depleting nanoplatform for cancer photodynamic therapy

Y Zhang, J Fang, S Ye, Y Zhao, A Wang, Q Mao… - Nature …, 2022 - nature.com
Hydrogen sulfide (H2S) as an important biological gasotransmitter plays a pivotal role in
many physiological and pathological processes. The sensitive and quantitative detection of …

Protein persulfidation: Rewiring the hydrogen sulfide signaling in cell stress response

B He, Z Zhang, Z Huang, X Duan, Y Wang, J Cao… - Biochemical …, 2023 - Elsevier
The past few decades have witnessed significant progress in the discovery of hydrogen
sulfide (H 2 S) as a ubiquitous gaseous signaling molecule in mammalian physiology, akin …

Sulfide regulation of cardiovascular function in health and disease

GK Kolluru, RE Shackelford, X Shen… - Nature Reviews …, 2023 - nature.com
Hydrogen sulfide (H2S) has emerged as a gaseous signalling molecule with crucial
implications for cardiovascular health. H2S is involved in many biological functions …

Reactive sulfur species and their significance in health and disease

M Iciek, A Bilska-Wilkosz, M Kozdrowicki… - Bioscience …, 2022 - portlandpress.com
Reactive sulfur species (RSS) have been recognized in the last two decades as very
important molecules in redox regulation. They are involved in metabolic processes and, in …

Protein S-sulfhydration: unraveling the prospective of hydrogen sulfide in the brain, vasculature and neurological manifestations

R Gupta, M Sahu, R Tripathi, RK Ambasta… - Ageing Research …, 2022 - Elsevier
Hydrogen sulfide (H 2 S) and hydrogen polysulfides (H 2 S n) are essential regulatory
signaling molecules generated by the entire body, including the central nervous system …

An updated insight into molecular mechanism of hydrogen sulfide in cardiomyopathy and myocardial ischemia/reperfusion injury under diabetes

HJ Sun, ZY Wu, XW Nie, XY Wang… - Frontiers in …, 2021 - frontiersin.org
Cardiovascular diseases are the most common complications of diabetes, and diabetic
cardiomyopathy is a major cause of people death in diabetes. Molecular, transcriptional …

[HTML][HTML] Hydrogen sulfide (H2S) signaling as a protective mechanism against endogenous and exogenous neurotoxicants

M Aschner, AV Skalny, T Ke, JBT da Rocha… - Current …, 2022 - ncbi.nlm.nih.gov
In view of the significant role of H 2 S in brain functioning, it is proposed that H2S may also
possess protective effects against adverse effects of neurotoxicants. Therefore, the objective …

Hydrogen Sulfide in Diabetic complications Revisited: the state of the art, challenges, and future directions

HJ Sun, SP Xiong, ZC Wang, XW Nie… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Diabetes and its related complications are becoming an increasing public
health problem that affects hundreds of millions of people globally. Increased disability and …