Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS

P Willner - Neuropsychobiology, 2005 - karger.com
The chronic mild stress (CMS) model of depression has high validity but has in the past
been criticized for being difficult to replicate. However, a large number of recent publications …

Chronic psychosocial factors and acute physiological responses to laboratory-induced stress in healthy populations: a quantitative review of 30 years of investigations.

Y Chida, M Hamer - Psychological bulletin, 2008 - psycnet.apa.org
Abstract [Correction Notice: An erratum for this article was reported in Vol 135 (5) of
Psychological Bulletin (see record 2009-12487-006). There is an error in Table 1. On p. 840 …

Neuroimmunological effects of physical exercise in depression

H Eyre, BT Baune - Brain, behavior, and immunity, 2012 - Elsevier
The search for an extended understanding of the causes of depression, and for the
development of additional effective treatments is highly significant. Clinical and pre-clinical …

Chronic mild stress induces behavioral and physiological changes, and may alter serotonin 1A receptor function, in male and cycling female rats

AJ Grippo, NR Sullivan, KJ Damjanoska, JW Crane… - …, 2005 - Springer
Rationale Interactions among stress, serotonin 1A (5-HT 1A) receptors, and the
hypothalamic–pituitary–adrenocortical (HPA) system have been proposed to influence the …

Chronic intermittent psychosocial stress (social defeat/overcrowding) in mice increases the severity of an acute DSS-induced colitis and impairs regeneration

SO Reber, F Obermeier, HR Straub, W Falk… - …, 2006 - academic.oup.com
Ulcerative colitis is a multifactorial disease, with immunological, genetic, and environmental
factors playing an important role in its pathogenesis. Here we investigated the …

Cognitive deficits in the rat chronic mild stress model for depression: relation to anhedonic-like responses

K Henningsen, JT Andreasen, EV Bouzinova… - Behavioural brain …, 2009 - Elsevier
The chronic mild stress (CMS) protocol is widely used to evoke depressive-like behaviours
in laboratory rats. The aim of the present study was to examine the effects of chronic stress …

Stress-related immune markers in depression: implications for treatment

MM Hughes, TJ Connor, A Harkin - International Journal of …, 2016 - academic.oup.com
Major depression is a serious psychiatric disorder; however, the precise biological basis of
depression still remains elusive. A large body of evidence implicates a dysregulated …

Acute and chronic stress exert opposing effects on antibody responses associated with changes in stress hormone regulation of T-lymphocyte reactivity

DM Silberman, MR Wald, AM Genaro - Journal of Neuroimmunology, 2003 - Elsevier
Here we show that stress exerts a differential effect on T-cell-dependent antibody
production. IgG production is augmented after acute stress and impaired in a chronic …

Magnetic resonance imaging and spectroscopy reveal differential hippocampal changes in anhedonic and resilient subtypes of the chronic mild stress rat model

RD y Palacios, A Campo, K Henningsen, M Verhoye… - Biological …, 2011 - Elsevier
BACKGROUND: Repeated exposure to mild stressors induces anhedonia—a core symptom
of major depressive disorder—in up to 70% of the stress-exposed rats, whereas the …

The physiological and behavioural impacts of and preference for an enriched environment in the eastern box turtle (Terrapene carolina carolina)

BC Case, GA Lewbart, PD Doerr - Applied Animal Behaviour Science, 2005 - Elsevier
The physiological and behavioural impact of, as well as preference for, enriched versus
barren environments was determined for captive eastern box turtles (Terrapene carolina …