Eph receptors are the largest family of receptor tyrosine kinases and mediate a myriad of
essential processes in humans from embryonic development to adult tissue homeostasis …

Glioblastoma multiforme (GBM) is the most aggressive type of primary brain tumor and is
associated with a poor clinical prognosis. Despite the progress in the understanding of the …

Triple-negative breast cancer (TNBC) is the most aggressive subtype of mammary
carcinoma. Here, we describe a case of an 81-year-old female diagnosed with ductal triple …

Glioblastoma is the most common malignant brain tumor. Efficient delivery of drugs targeting
glioblastomas remains a challenge. Ephrin type-A receptor 3 (EPHA3) tyrosine kinase …

Eph receptor tyrosine kinases play critical functions during development, in the formation of
tissue and organ borders, and the vascular and neural systems. Uniquely among tyrosine …

Numerous studies have revealed that cancer patients are more likely to develop severe
Coronavirus disease-2019 (COVID-19), which can cause mortality, as well as cancer …

Introduction Erythropoietin-producing human hepatocellular (Eph) receptors are among the
largest family of tyrosine kinases that are divided into two classes: EphA and EphB …

It is well established that the Eph/ephrin system plays a central role in the embryonic
development, with minor implications in the physiology of the adult. However, it is …

Simple Summary A rapidly emerging new approach to treat cancer involves collection of
patient immune white blood cells and genetic re-programming of the cells to express a new …

Simple Summary We have identified the cell guidance receptor EphA3 on distinct
stromal/fibroblast-like cell types in the tumour microenvironment (TME) that promote growth …