In-host models have been essential for understanding the dynamics of virus infection inside
an infected individual. When used together with biological data, they provide insight into …

Objective The objective of this study is to conduct a systematic review of multi-scale HIV
immunoepidemiological models to improve our understanding of the synergistic impact …

Modelling of infectious disease systems has entered a new era in which disease modellers
are increasingly turning to multiscale modelling to extend traditional modelling frameworks …

Despite the fact that mathematical applications to biology and medicine have been
mentioned since the eighteenth century [1][or even earlier, if we think of Fibonacci's example …

Strategies to control HIV-1 replication without antiviral therapy are needed to achieve a
functional cure. To exploit the innate antiviral function of restriction factor cytidine deaminase …

Abstract The 'Berlin Patient', who maintains suppressed levels of HIV viremia in the absence
of antiretroviral therapy, continues to be a standard bearer in HIV eradication research …

Over the past decade, studies applying data-driven modeling approaches have
demonstrated significant contributions toward the integrative understanding of multivariate …

There are many challenges to coupling the macroscale to the microscale in temporal or
spatial contexts. In order to examine effects of an individual movement and spatial control …

Human immunodeficiency virus-1 (HIV-1) dynamics reflect an intricate balance within the
viruses' host. The virus relies on host replication factors, but must escape or counter its host's …

The interplay between the innate immune system restriction factor APOBEC3G and the HIV
protein Vif is a key host-retrovirus interaction. APOBEC3G can counteract HIV infection in at …