Citrus fruits have been a commercially important crop for thousands of years. In addition,
Citrus essential oils are valuable in the perfume, food, and beverage industries, and have …

Phenolics, which are secondary metabolites of plants, exhibit remarkable bioactivities. In this
contribution, we have focused on their protective effect against chronic diseases rather than …

Cancer is one of the leading health hazards and the prominent cause of death in the world.
A number of anticancer agents are currently in clinical practice and used for treatment of …

Coumarin heterocyclic derivatives: chemical synthesis and biological activity - Natural Product
Reports (RSC Publishing) DOI:10.1039/C4NP00162A Royal Society of Chemistry View PDF …

The Keap1/Nrf2/ARE system is a central defensive mechanism against oxidative stress
which plays a key role in the pathogenesis and progression of many diseases. Nrf2 is a …

Acetylcholinesterase (AChE) enzyme inhibition is an important target for the management of
Alzheimer disease (AD) and AChE inhibitors are the main stay drugs for its management …

Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

Naturally occurring coumarins, having wide spectrum of activities such as antioxidant, anti-
inflammatory, anticancer, MAO-B inhibitory and antimicrobial, are frequently used by the …

Esculetin is a natural dihydroxy coumarin; it is mainly extracted from twig skin and the trunk
bark of the Chinese herbal medicine Fraxinus rhynchophylla Hance. Emerging evidence …

Tuberculosis (TB) is still a challenging worldwide health problem and mycobacterium
tuberculosis (MTB) remains one of the most deadly human pathogens. TB is the second …