The biofilm matrix can be considered to be a shared space for the encased microbial cells,
comprising a wide variety of extracellular polymeric substances (EPS), such as …

Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …

Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …

Despite abundant research in the field of antifungal drug discovery, fungal infections remain
a significant healthcare burden. There is an emerging need for the development of novel …

Highlights•Biofilm formation is a major contributor to pathogenesis during Candida
infection.•C. albicans biofilm formation is a multi-step, highly regulated process.•Cells in …

Compared to mono-species biofilm, biofilms formed by cross-kingdom pathogens are more
refractory to conventional antibiotics, thus complicating clinical treatment and causing …

The ability of Candida spp. to form biofilms is crucial for its pathogenicity, and thus, it should
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …

Pathogenic microorganisms have adapted different strategies during the course of time to
invade host defense mechanisms and overcome the effect of potent antibiotics. The …

Candida auris has emerged as a significant global nosocomial pathogen. This is primarily
due to its antifungal resistance profile but also its capacity to form adherent biofilm …