Integrons: past, present, and future
MR Gillings - Microbiology and molecular biology reviews, 2014 - Am Soc Microbiol
Integrons are versatile gene acquisition systems commonly found in bacterial genomes.
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …
Dissemination of antibiotic resistance genes (ARGs) via integrons in Escherichia coli: a risk to human health
S Zhang, M Abbas, MU Rehman, Y Huang, R Zhou… - Environmental …, 2020 - Elsevier
With the induction of various emerging environmental contaminants such as antibiotic
resistance genes (ARGs), environment is considered as a key indicator for the spread of …
resistance genes (ARGs), environment is considered as a key indicator for the spread of …
SOS, the formidable strategy of bacteria against aggressions
Z Baharoglu, D Mazel - FEMS microbiology reviews, 2014 - academic.oup.com
The presence of an abnormal amount of single-stranded DNA in the bacterial cell constitutes
a genotoxic alarm signal that induces the SOS response, a broad regulatory network found …
a genotoxic alarm signal that induces the SOS response, a broad regulatory network found …
Inactivation of antibiotics and the dissemination of resistance genes
J Davies - Science, 1994 - science.org
The emergence of multidrug-resistant bacteria is a phenomenon of concern to the clinician
and the pharmaceutical industry, as it is the major cause of failure in the treatment of …
and the pharmaceutical industry, as it is the major cause of failure in the treatment of …
Gene cassettes and cassette arrays in mobile resistance integrons
Gene cassettes are small mobile elements, consisting of little more than a single gene and
recombination site, which are captured by larger elements called integrons. Several …
recombination site, which are captured by larger elements called integrons. Several …
Pathogenicity islands and the evolution of microbes
J Hacker, JB Kaper - Annual Reviews in Microbiology, 2000 - annualreviews.org
▪ Abstract Virulence factors of pathogenic bacteria (adhesins, toxins, invasins, protein
secretion systems, iron uptake systems, and others) may be encoded by particular regions of …
secretion systems, iron uptake systems, and others) may be encoded by particular regions of …
PCR mapping of integrons reveals several novel combinations of resistance genes
C Levesque, L Piche, C Larose… - Antimicrobial agents and …, 1995 - Am Soc Microbiol
The integron is a new type of mobile element which has evolved by a site-specific
recombinational mechanism. Integrons consist of two conserved segments of DNA …
recombinational mechanism. Integrons consist of two conserved segments of DNA …
Mobile gene cassettes and integrons: capture and spread of genes by site‐specific recombination
RM Hall, CM Collis - Molecular microbiology, 1995 - Wiley Online Library
An integron is a genetic unit that includes the determinants of the components of a site‐
specific recombination system capable of capturing and mobilizing genes that are contained …
specific recombination system capable of capturing and mobilizing genes that are contained …
Transposon Tn21, Flagship of the Floating Genome
CA Liebert, RM Hall, AO Summers - Microbiology and molecular …, 1999 - Am Soc Microbiol
The transposon Tn21 and a group of closely related transposons (the Tn21 family) are
involved in the global dissemination of antibiotic resistance determinants in gram-negative …
involved in the global dissemination of antibiotic resistance determinants in gram-negative …