Type 1 diabetes in diverse ancestries and the use of genetic risk scores

MJ Redondo, CR Gignoux, D Dabelea… - The Lancet Diabetes & …, 2022 - thelancet.com
Over 75 genetic loci within and outside of the HLA region influence type 1 diabetes risk.
Genetic risk scores (GRS), which facilitate the integration of complex genetic information …

[图书][B] Ecosocial theory, embodied truths, and the people's health

N Krieger - 2021 - books.google.com
From public health luminary Nancy Krieger comes a revolutionary way of addressing health
justice and the embodied truths of lived experience. Since the 1700s, fierce debates in …

Genotyping, sequencing and analysis of 140,000 adults from Mexico City

A Ziyatdinov, J Torres, J Alegre-Díaz, J Backman… - Nature, 2023 - nature.com
Abstract The Mexico City Prospective Study is a prospective cohort of more than 150,000
adults recruited two decades ago from the urban districts of Coyoacán and Iztapalapa in …

Founder mutations and rare disease in the Arab world

D Marafi - Disease Models & Mechanisms, 2024 - journals.biologists.com
Founder mutations are disease-causing variants that occur frequently in geographically or
culturally isolated groups whose shared ancestor (s) carried the pathogenic variant. While …

Dementia in Latin America: paving the way toward a regional action plan

MA Parra, S Baez, L Sedeño… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract Across Latin American and Caribbean countries (LACs), the fight against dementia
faces pressing challenges, such as heterogeneity, diversity, political instability, and …

Toward a fine-scale population health monitoring system

GM Belbin, S Cullina, S Wenric, ER Soper… - Cell, 2021 - cell.com
Understanding population health disparities is an essential component of equitable
precision health efforts. Epidemiology research often relies on definitions of race and …

Rapid adaptation to malaria facilitated by admixture in the human population of Cabo Verde

I Hamid, KL Korunes, S Beleza, A Goldberg - Elife, 2021 - elifesciences.org
Humans have undergone large migrations over the past hundreds to thousands of years,
exposing ourselves to new environments and selective pressures. Yet, evidence of ongoing …

Biomarkers for dementia in Latin American countries: Gaps and opportunities

MA Parra, P Orellana, T Leon, CG Victoria… - Alzheimer's & …, 2023 - Wiley Online Library
Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC)
countries remains a serious barrier. Here, we reported a survey to explore the ongoing work …

Metacognitive reflections on essentialism during the learning of the relationship between biology and the human race

G Pérez, LG Galli - Metacognition and Learning, 2024 - Springer
Developing metacognition in students is essential for fostering critical thinking in school.
One of the skills necessary to achieve this goal is the cultivation of metacognitive vigilance …

Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes

MA Nieves-Colón, KMB Rivera, K Sandoval… - The American Journal of …, 2022 - cell.com
Preeclampsia is a multi-organ complication of pregnancy characterized by sudden
hypertension and proteinuria that is among the leading causes of preterm delivery and …