Osteocytes in bone aging: Advances, challenges, and future perspectives
Osteocytes play a critical role in maintaining bone homeostasis and in regulating skeletal
response to hormones and mechanical loading. Substantial evidence have demonstrated …
response to hormones and mechanical loading. Substantial evidence have demonstrated …
[HTML][HTML] Fractures in patients with CKD—diagnosis, treatment, and prevention: a review by members of the European Calcified Tissue Society and the European …
A Pimentel, P Urena-Torres, MC Zillikens, J Bover… - Kidney international, 2017 - Elsevier
Mineral and bone disease is omnipresent in patients with chronic kidney disease (CKD) and
leads to a diverse range of clinical manifestations, including bone pain and fractures. The …
leads to a diverse range of clinical manifestations, including bone pain and fractures. The …
Quantifying the osteocyte network in the human skeleton
PR Buenzli, NA Sims - Bone, 2015 - Elsevier
Osteocytes form an extensive cellular network throughout the hard tissue matrix of the
skeleton, which is known to regulate skeletal structure. However due to limitations in …
skeleton, which is known to regulate skeletal structure. However due to limitations in …
Disrupted osteocyte connectivity and pericellular fluid flow in bone with aging and defective TGF-β signaling
CA Schurman, SW Verbruggen… - Proceedings of the …, 2021 - National Acad Sciences
Skeletal fragility in the elderly does not simply result from a loss of bone mass. However, the
mechanisms underlying the concurrent decline in bone mass, quality, and …
mechanisms underlying the concurrent decline in bone mass, quality, and …
[HTML][HTML] Biodegradable magnesium barrier membrane used for guided bone regeneration in dental surgery
P Rider, ŽP Kačarević, A Elad, D Tadic, D Rothamel… - Bioactive materials, 2022 - Elsevier
Barrier membranes are commonly used as part of the dental surgical technique guided bone
regeneration (GBR) and are often made of resorbable collagen or non-resorbable materials …
regeneration (GBR) and are often made of resorbable collagen or non-resorbable materials …
The small world of osteocytes: connectomics of the lacuno-canalicular network in bone
P Kollmannsberger, M Kerschnitzki, F Repp… - New Journal of …, 2017 - iopscience.iop.org
Osteocytes and their cell processes reside in a large, interconnected network of voids
pervading the mineralized bone matrix of most vertebrates. This osteocyte lacuno …
pervading the mineralized bone matrix of most vertebrates. This osteocyte lacuno …
Techniques to assess bone ultrastructure organization: orientation and arrangement of mineralized collagen fibrils
M Georgiadis, R Müller… - Journal of the Royal …, 2016 - royalsocietypublishing.org
Bone's remarkable mechanical properties are a result of its hierarchical structure. The
mineralized collagen fibrils, made up of collagen fibrils and crystal platelets, are bone's …
mineralized collagen fibrils, made up of collagen fibrils and crystal platelets, are bone's …
[HTML][HTML] Characterization and distribution of mechanically competent mineralized tissue in micropores of β-tricalcium phosphate bone substitutes
Although bone formation around and within implants has been intensively studied, the role
of pores and pore geometry is still debated. Notwithstanding studies reporting the formation …
of pores and pore geometry is still debated. Notwithstanding studies reporting the formation …
[HTML][HTML] A novel RGB-trichrome staining method for routine histological analysis of musculoskeletal tissues
F Gaytan, C Morales, C Reymundo… - Scientific reports, 2020 - nature.com
Morphometry and histology are essential approaches for investigation and diagnosis of
musculo-skeletal disorders. Despite the advent of revolutionary methods of image analysis …
musculo-skeletal disorders. Despite the advent of revolutionary methods of image analysis …
Lactation‐induced changes in the volume of osteocyte lacunar‐canalicular space alter mechanical properties in cortical bone tissue
S Kaya, J Basta‐Pljakic… - Journal of Bone and …, 2017 - academic.oup.com
Osteocytes can remove and remodel small amounts of their surrounding bone matrix
through osteocytic osteolysis, which results in increased volume occupied by lacunar and …
through osteocytic osteolysis, which results in increased volume occupied by lacunar and …