The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

Cryptococcus neoformans Infection in the Central Nervous System: The Battle between Host and Pathogen

Y Chen, ZW Shi, AB Strickland, M Shi - Journal of Fungi, 2022 - mdpi.com
Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Bacterial-fungal metabolic interactions within the microbiota and their potential relevance in human health and disease: a short review

A Lapiere, ML Richard - Gut Microbes, 2022 - Taylor & Francis
The composition of the microbiota is the focus of many recent publications describing the
effects of the microbiota on host health. In recent years, research has progressed further …

Extracellular Vesicles from Cryptococcus neoformans Modulate Macrophage Functions

DL Oliveira, CG Freire-de-Lima… - Infection and …, 2010 - Am Soc Microbiol
Cryptococcus neoformans and distantly related fungal species release extracellular vesicles
that traverse the cell wall and contain a varied assortment of components, some of which …

Cryptococcal interactions with the host immune system

K Voelz, RC May - Eukaryotic cell, 2010 - Am Soc Microbiol
Opportunistic pathogens have become of increasing medical importance over the last
decade due to the AIDS pandemic. Not only is cryptococcosis the fourth-most-common fatal …

Cryptococcus

SS Li, CH Mody - Proceedings of the American Thoracic Society, 2010 - atsjournals.org
Cryptococcus is a unique environmental fungus. Among the more than three dozen species
of Cryptococcus, only C. neoformans and C. gattii commonly cause disease. Although many …

Involvement of CD14, Toll-Like Receptors 2 and 4, and MyD88 in the Host Response to the Fungal Pathogen Cryptococcus neoformans In Vivo

LE Yauch, MK Mansour, S Shoham… - Infection and …, 2004 - Am Soc Microbiol
The major capsular polysaccharide of Cryptococcus neoformans, glucuronoxylomannan
(GXM), is recognized by Toll-like receptor 2 (TLR2), TLR4, and CD14. In these studies, mice …

Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome

CM Leopold Wager, CR Hole, KL Wozniak… - Frontiers in …, 2016 - frontiersin.org
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

[HTML][HTML] C-type lectin Langerin is a β-glucan receptor on human Langerhans cells that recognizes opportunistic and pathogenic fungi

MAWP de Jong, LEM Vriend, B Theelen, ME Taylor… - Molecular …, 2010 - Elsevier
Langerhans cells (LCs) lining the stratified epithelia and mucosal tissues are the first antigen
presenting cells to encounter invading pathogens, such as viruses, bacteria and fungi …

Role of Dendritic Cells and Alveolar Macrophages in Regulating Early Host Defense against Pulmonary Infection with Cryptococcus neoformans

JJ Osterholzer, JE Milam, GH Chen… - Infection and …, 2009 - Am Soc Microbiol
Successful pulmonary clearance of the encapsulated yeast Cryptococcus neoformans
requires a T1 adaptive immune response. This response takes up to 3 weeks to fully …