COVID-19-associated fungal infections

M Hoenigl, D Seidel, R Sprute, C Cunha… - Nature …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an
important complication in a substantial number of critically ill, hospitalized patients with …

The rapid emergence of antifungal-resistant human-pathogenic fungi

SR Lockhart, A Chowdhary, JAW Gold - Nature Reviews Microbiology, 2023 - nature.com
During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …

The antifungal pipeline: fosmanogepix, ibrexafungerp, olorofim, opelconazole, and rezafungin

M Hoenigl, R Sprute, M Egger, A Arastehfar… - Drugs, 2021 - Springer
The epidemiology of invasive fungal infections is changing, with new populations at risk and
the emergence of resistance caused by the selective pressure from increased usage of …

[HTML][HTML] COVID-19–associated mucormycosis: a systematic review and meta-analysis of 958 cases

L Özbek, U Topçu, M Manay, BH Esen… - Clinical Microbiology …, 2023 - Elsevier
Background Mucormycosis, a rare fungal infection, has shown an increase in the number of
reported cases during the COVID-19 pandemic. Objectives To provide a comprehensive …

A visual and comprehensive review on COVID-19-associated pulmonary aspergillosis (CAPA)

S Feys, MP Almyroudi, R Braspenning, K Lagrou… - Journal of Fungi, 2021 - mdpi.com
Coronavirus disease 19 (COVID-19)-associated pulmonary aspergillosis (CAPA) is a severe
fungal infection complicating critically ill COVID-19 patients. Numerous retrospective and …

Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study

S Feys, SM Gonçalves, M Khan, S Choi… - The Lancet …, 2022 - thelancet.com
Background Influenza-associated pulmonary aspergillosis (IAPA) and COVID-19-associated
pulmonary aspergillosis (CAPA) affect about 15% of critically ill patients with influenza or …

Invasive pulmonary aspergillosis among intubated patients with SARS-CoV-2 or influenza pneumonia: a European multicenter comparative cohort study

A Rouzé, E Lemaitre, I Martin-Loeches, P Povoa… - Critical Care, 2022 - Springer
Background Recent multicenter studies identified COVID-19 as a risk factor for invasive
pulmonary aspergillosis (IPA). However, no large multicenter study has compared the …

Alterations in the respiratory tract microbiome in COVID-19: current observations and potential significance

C Merenstein, FD Bushman, RG Collman - Microbiome, 2022 - Springer
SARS-CoV-2 infection causes COVID-19 disease, which can result in consequences
ranging from undetectable to fatal, focusing attention on the modulators of outcomes. The …

Prevalence of COVID-19-associated pulmonary aspergillosis: critical review and conclusions

M Egger, L Bussini, M Hoenigl, M Bartoletti - Journal of Fungi, 2022 - mdpi.com
First reports of cases and case series of COVID-19-associated pulmonary aspergillosis
(CAPA) emerged during the first months of the pandemic. Prevalence rates varied widely …

Fungal infection profile in critically ill COVID-19 patients: a prospective study at a large teaching hospital in a middle-income country

EM Negm, MS Mohamed, RA Rabie, WS Fouad… - BMC Infectious …, 2023 - Springer
Background Critically ill COVID-19 patients are highly susceptible to opportunistic fungal
infection due to many factors, including virus-induced immune dysregulation, host-related …