The bio-manufacturing industry, along with other process industries, now has the opportunity
to be engaged in the latest industrial revolution, also known as Industry 4.0. To successfully …

Fish oil is a nutritious product, mainly due its omega-3 polyunsaturated fatty acids (ω-3
PUFA) content that is attractive for its health benefits. Fish oil is discarded as a waste in …

Electroreduction systems to convert CO2 into CO via Ag electrodes have been intensely
studied as a means of producing carbon-neutral fuels or chemical products. However …

The conceptual process design of novel bioprocesses in biorefinery setups is an important
task, which remains yet challenging due to several limitations. We propose a novel …

Pump-as-turbine (PAT) technology permits two operating states—as a pump or turbine,
depending on the demand. Nevertheless, designing the geometrical components to suit …

Bayesian hybrid models fuse physics-based insights with machine learning constructs to
correct for systematic bias. In this paper, we compare Bayesian hybrid models against …

Abstract Model discrimination identifies a mathematical model that usefully explains and
predicts a given system's behaviour. Researchers will often have several models, ie …

This study presents a methodology with tools integration to apply advanced uncertainty
propagation and sensitivity analysis in connection with commercial process simulation …

Accurate simulations are of fundamental importance for process engineers, but most modern
simulation software is often inflexible, and cannot be easily integrated into new applications …

We address the problem of site-wide operational optimization of production plants in the
context of Industry 4.0 with an emphasis on sensor data-driven approaches. A multi-plant …