Three decades of valproate: a current model for studying autism Spectrum disorder

D Zarate-Lopez, AL Torres-Chávez… - Current …, 2024 - benthamdirect.com
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …

Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk

S Kumar, K Reynolds, Y Ji, R Gu, S Rai… - Journal of …, 2019 - Springer
Background The development of an autistic brain is a highly complex process as evident
from the involvement of various genetic and non-genetic factors in the etiology of the autism …

Autism‐related behaviors in the cyclooxygenase‐2‐deficient mouse model

CT Wong, I Bestard‐Lorigados… - Genes, Brain and …, 2019 - Wiley Online Library
Prostaglandin E2 (PGE2) is an endogenous lipid molecule involved in normal brain
development. Cyclooxygenase‐2 (COX2) is the main regulator of PGE2 synthesis. Emerging …

Prostaglandin E2 alters Wnt-dependent migration and proliferation in neuroectodermal stem cells: implications for autism spectrum disorders

CT Wong, E Ahmad, H Li, DA Crawford - Cell Communication and …, 2014 - Springer
Abstract Prostaglandin E2 (PGE 2) is a natural lipid-derived molecule that is involved in
important physiological functions. Abnormal PGE 2 signalling has been associated with …

Roles of Wnt signaling pathway and ROR2 receptor in embryonic development: an update review article

R Guo, QS Xing - Epigenetics Insights, 2022 - journals.sagepub.com
The Wnt family is a large class of highly conserved cysteine-rich secretory glycoproteins that
play a vital role in various cellular and physiological courses through different signaling …

Genome-wide association study for autism spectrum disorder in Taiwanese Han population

PH Kuo, LC Chuang, MH Su, CH Chen, CH Chen… - PLoS …, 2015 - journals.plos.org
Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder with strong
genetic components. Several recent genome-wide association (GWA) studies in Caucasian …

Wnt/β-catenin pathway and cell adhesion deregulation in CSDE1-related intellectual disability and autism spectrum disorders

E El Khouri, J Ghoumid, D Haye, F Giuliano… - Molecular …, 2021 - nature.com
Among the genetic factors playing a key role in the etiology of intellectual disabilities (IDs)
and autism spectrum disorders (ASDs), several encode RNA-binding proteins (RBPs). In this …

Examining the Transition from Single Words to Phrase Speech in Children with ASD: A Systematic Review

K Byrne, K Sterrett, C Lord - Clinical Child and Family Psychology Review, 2024 - Springer
Abstract “Functional speech” by 5 years of age is widely established as increasing the
probability of long-term positive outcomes across a range of domains for autistic individuals …

Master regulators of neurogenesis: the dynamic roles of Ephrin receptors across diverse cellular niches

D Rasool, A Jahani-Asl - Translational Psychiatry, 2024 - nature.com
The ephrin receptors (EphRs) are the largest family of receptor tyrosine kinases (RTKs) that
are abundantly expressed in the developing brain and play important roles at different …

Neurodevelopment in schizophrenia: the role of the wnt pathways

I Panaccione, F Napoletano… - Current …, 2013 - ingentaconnect.com
Objectives. To review the role of Wnt pathways in the neurodevelopment of schizophrenia.
Methods: Systematic PubMed search, using as keywords all the terms related to the Wnt …