Triggering biological processes: methods and applications of photocaged peptides and proteins

AE Mangubat-Medina, ZT Ball - Chemical Society Reviews, 2021 - pubs.rsc.org
There has been a significant push in recent years to deploy fundamental knowledge and
methods of photochemistry toward biological ends. Photoreactive groups have enabled …

[HTML][HTML] The development and application of opto-chemical tools in the zebrafish

Z Feng, B Ducos, P Scerbo, I Aujard, L Jullien… - Molecules, 2022 - mdpi.com
The zebrafish is one of the most widely adopted animal models in both basic and
translational research. This popularity of the zebrafish results from several advantages such …

Controlling the oligomerization state of Aβ-derived peptides with light

PJ Salveson, S Haerianardakani… - Journal of the …, 2018 - ACS Publications
A key challenge in studying the biological and biophysical properties of amyloid-forming
peptides is that they assemble to form heterogeneous mixtures of soluble oligomers and …

Site-specific reversible protein and peptide modification: transglutaminase-catalyzed glutamine conjugation and bioorthogonal light-mediated removal

KR Moulton, A Sadiki, BN Koleva… - Bioconjugate …, 2019 - ACS Publications
Dynamic photoswitches in proteins that impart spatial and temporal control are important to
manipulate and study biotic and abiotic processes. Nonetheless, approaches to install these …

Photoresponsive peptide materials: Spatiotemporal control of self-assembly and biological functions

K Matsuura, H Inaba - Biophysics Reviews, 2023 - pubs.aip.org
Peptides work as both functional molecules to modulate various biological phenomena and
self-assembling artificial materials. The introduction of photoresponsive units to peptides …

[HTML][HTML] Synthesis of chemical tools to improve water solubility and promote the delivery of salinomycin to cancer cells

L Awad - Experimental and Therapeutic Medicine, 2020 - spandidos-publications.com
Chemotherapy and radiation are unable to eliminate all cancer cells, particularly apoptosis‑
resistant cancer cells, despite their ability to kill cancer cluster cells. Thus, it is important to …

In vitro and in vivo Evaluation of Chemically Synthesized, Receptor-Biased Interleukin-4 and Photocaged Variants

M Ninomiya, C Egholm, D Breu, O Boyman, J Bode - 2024 - chemrxiv.org
Interleukin-4 (IL-4) is a cytokine that plays a central role in type 2 immune responses and is
involved in regulating pleiotropic actions in our body by engaging multiple different IL-4 …

A clickable glutamine (CliQ) derivative for the traceless reversible modification of peptides and proteins

SD Whedon, MK Parker, EL Tyson… - Chemical …, 2019 - pubs.rsc.org
The Cu (I)-mediated click reaction of proteins with affinity tags enables their selective
isolation from complex mixtures. However, irreversible protein modification limits the …

THMs precursor removal efficiency from different wastewater treatment technologies effluents

M Qurie, L Awad, A Kanan - 2018 - dspace.alquds.edu
Treated wastewater is one of the critical practices of sustainable water management. In
Palestinian authority region different wastewater technologies are used to produce variety of …

Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates

ZS Zhou, G O'doherty, S Liu, KR Moulton… - US Patent …, 2021 - Google Patents
1115433 B1 12/2004 1645907 A1 4/2006 1757314 A1 2/2007 3004434 B1 4/2016 2473627
B1 12/2016 2012520863 A 9/2012 2016517694 A 6/2016 2000016818 Al 3/2000 …