Adiponectin regulates metabolism through blood glucose control and fatty acid oxidation,
partly mediated by downstream effects of adiponectin signaling in skeletal muscle. More …

Obesity is a chronic and complex medical condition associated with a large number of
complications affecting most organs and systems through multiple pathways. Strategies for …

Within adipose tissue (AT), immune cells and parenchymal cells closely interact creating a
complex microenvironment. In obesity, immune cell derived inflammation contributes to …

Circulating branched-chain amino acids (BCAAs) associate with insulin resistance and type
2 diabetes. 3-Hydroxyisobutyrate (3-HIB) is a catabolic intermediate of the BCAA valine. In …

This study compares two typical strains: Chinese local excellent meat quality of Jiaxing
Black (JXB) Pig and quadratic crossbred pig strain Duroc× Duroc× Berkshire× Jiaxing Black …

Elucidation of mechanisms that govern lipid storage, oxidative stress, and insulin resistance
may lead to improved therapeutic options for type 2 diabetes and other obesity-related …

Impacts of weight cycling on C1q/tumor necrosis factor (TNF)-related protein-3 (CTRP3)
expression, adipose tissue inflammation and insulin sensitivity in C57BL/6J mice were …

Mechanisms that control 'beige/brite'thermogenic adipose tissue development may be
harnessed to improve human metabolic health. To define these mechanisms, we developed …

Dieting often leads to body weight cycling involving repeated weight loss and regain.
However, little information is available regarding rapid-response serum markers of …

Background Adipose tissue plays a crucial role in diet-and obesity-related insulin resistance,
with implications for several metabolic diseases. Identification of novel target genes and …