Since their introduction 15 years ago, retinoids have been increasingly used for topical and
systemic treatment of psoriasis and other hyperkeratotic and parakeratotic skin disorders …

The determination of retinol (vitamin A) and its metabolites, as well as synthetic retinoids, in
biological samples is a challenging task due to the sensitivity of these compounds to light …

Acitretin has recently been introduced to replace etretinate in the treatment of severe
psoriasis due to a considerable shorter terminal half-life. The previously recommended 2 …

Background Acitretin has replaced etretinate in the treatment of various disorders of
keratinization due to a considerably shorter terminal half‐life. Possible esterification of …

This article reviews the determination of retinoic acids and their metabolites (first-generation
retinoids), aromatic retinoids (second generation) and arotinoids (third generation) in …

The term ''retinoids''includes both naturally occurring molecules and also synthetic
compounds showing biological activities that are characteristic for vitamin A. The current …

The aromatic retinoic acid derivative etretin has recently been introduced in the treatment of
severe psoriasis and other dyskeratoses. Hitherto, the use of the carboxylic acid ester …

The synthetic retinoic acid derivative acitretin has recently been introduced for the treatment
of severe psoriasis. Hitherto, the use of the carboxylic acid ester analogue, etretinate, has …

Background Isotretinoin is effective in the treatment of severe acne and rosacea. Both parent
drug and its main metabolite 4‐oxo‐isotretinoin are potentially teratogenic compounds and …

The most useful new publication in the field of carotenoids is an up-to-date 'Key to
Carotenoids';'this supersedes the first edition, 2 which was published in 1976. This book …