Molecular mechanisms of antibiotic resistance
Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly
common and are causing a global health crisis. Antibiotic resistance is encoded by several …
common and are causing a global health crisis. Antibiotic resistance is encoded by several …
Update on infections caused by Stenotrophomonas maltophilia with particular attention to resistance mechanisms and therapeutic options
Stenotrophomonas maltophilia is a Gram-negative, biofilm-forming bacterium. Although
generally regarded as an organism of low virulence, S. maltophilia is an emerging multi …
generally regarded as an organism of low virulence, S. maltophilia is an emerging multi …
A review on cell wall synthesis inhibitors with an emphasis on glycopeptide antibiotics
Cell wall biosynthesis inhibitors (CBIs) have historically been one of the most effective
classes of antibiotics. They are the most extensively used class of antibiotics and their …
classes of antibiotics. They are the most extensively used class of antibiotics and their …
Task force on management and prevention of Acinetobacter baumannii infections in the ICU
Introduction Acinetobacter baumannii constitutes a dreadful problem in many ICUs
worldwide. The very limited therapeutic options available for these organisms are a matter of …
worldwide. The very limited therapeutic options available for these organisms are a matter of …
Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies
J Gibb, DW Wong - Antibiotics, 2021 - mdpi.com
Stenotrophomonas maltophilia is an urgent global threat due to its increasing incidence and
intrinsic antibiotic resistance. Antibiotic development has focused on carbapenem-resistant …
intrinsic antibiotic resistance. Antibiotic development has focused on carbapenem-resistant …
Recent advances and perspectives in the design and development of polymyxins
F Rabanal, Y Cajal - Natural product reports, 2017 - pubs.rsc.org
Covering: 1947-early 2017, particularly from 2005-early 2017 The rise of bacterial
pathogens with acquired resistance to almost all available antibiotics is becoming a serious …
pathogens with acquired resistance to almost all available antibiotics is becoming a serious …
Battle against vancomycin-resistant bacteria: recent developments in chemical strategies
Vancomycin, a natural glycopeptide antibiotic, was used as the antibiotic of last resort for the
treatment of multidrug-resistant Gram-positive bacterial infections. However, almost 30 years …
treatment of multidrug-resistant Gram-positive bacterial infections. However, almost 30 years …
Emerging roles of glycopeptide antibiotics: Moving beyond gram-positive bacteria
Glycopeptides, a class of cell wall biosynthesis inhibitors, have been the antibiotics of choice
against drug-resistant Gram-positive bacterial infections. Their unique mechanism of action …
against drug-resistant Gram-positive bacterial infections. Their unique mechanism of action …
In vitro synergy of polymyxins with other antibiotics for Acinetobacter baumannii: a systematic review and meta-analysis
W Ni, X Shao, X Di, J Cui, R Wang, Y Liu - International journal of …, 2015 - Elsevier
In order to provide preliminary guidance for rational antibiotic combination therapy in the
clinic, a systematic review and meta-analysis was performed to evaluate the in vitro …
clinic, a systematic review and meta-analysis was performed to evaluate the in vitro …
Synergistic combinations of polymyxins
JR Lenhard, RL Nation, BT Tsuji - International journal of antimicrobial …, 2016 - Elsevier
The proliferation of extensively drug-resistant Gram-negative pathogens has necessitated
the therapeutic use of colistin and polymyxin B. However, treatment failures with polymyxin …
the therapeutic use of colistin and polymyxin B. However, treatment failures with polymyxin …