A simple, primary amine bearing a C10H15 alkyl residue was found to display potent anti-
Influenza A properties in 1964. 1 Soon thereafter, antiviral activity of this amine was found …

Mitochondria are the cells' powerhouse, but also their suicidal weapon store. Dozens of
lethal signal transduction pathways converge on mitochondria to cause the permeabilization …

Irrespective of the morphological features of end-stage cell death (that may be apoptotic,
necrotic, autophagic, or mitotic), mitochondrial membrane permeabilization (MMP) is …

Mitochondrial control of cell death | Nature Medicine Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

The genus Propionibacterium is composed of dairy and cutaneous bacteria which produce
short-chain fatty acids (SCFA), mainly propionate and acetate, by fermentation. Here, we …

Mitochondrial membrane permeabilization is a critical event in the process leading to
physiologic or chemotherapy-induced apoptosis (programmed cell death). This …

Mitochondria are required for cellular survival, yet can also orchestrate cell death. The
peculiar biochemical properties of these organelles, which are intimately linked to their …

Purpose: Cisplatin adducts to nuclear DNA (nDNA) are felt to be the molecular lesions that
trigger apoptosis, but the mechanism linking nDNA adduct formation and cell death is …

One of the mechanisms by which chemotherapeutics destroy cancer cells is by inducing
apoptosis. Apoptosis can be activated through several different signalling pathways, but …

• Introduction• Mitochondria and cell death• Mitochondrial outer membrane permeabilization
(MOMP): point of no return‐MOMP by BCL‐2 family proteins‐MOMP by permeability …