A major approach for immunologic intervention in tuberculosis involves redirecting the
outcome of the host immune response from the induction of disease to pathogen control …

The body is exposed to foreign pathogens every day, but remarkably, most pathogens are
effectively cleared by the innate immune system without the need to invoke the adaptive …

Background Insertion sequences (IS) are small transposable elements, commonly found in
bacterial genomes. Identifying the location of IS in bacterial genomes can be useful for a …

Tuberculosis is a highly contagious disease caused by Mycobacterium tuberculosis (Mtb),
which is one of the prominent reasons for the death of millions worldwide. The bacterium …

Tuberculosis (TB) remains a prominent health concern worldwide. Besides extensive
research and vaccinations available, attempts to control the pandemic are cumbersome due …

The functions of eicosanoids, a family of potent biologically active lipid mediators, are not
restricted to inflammatory responses and they also act as mediators of the pathogenesis …

In the context of pulmonary infection, both hosts and pathogens have evolved a multitude of
mechanisms to regulate the process of host cell death. The host aims to rapidly induce an …

Alveolar macrophages are the main line of innate immune response against M. tuberculosis
(Mtb) infection. However, these cells serve as the major intracellular niche for Mtb enhancing …

Tuberculosis caused by Mycobacterium tuberculosis continues to pose a serious global
health threat. The attenuated Mycobacterium bovis bacillus Calmette–Guérin, as the only …

Prostaglandin E 2 (PGE 2) suppresses macrophage effector mechanisms; however, little is
known about the function of PGD 2 in infected alveolar macrophages (AMs). Using serum …