[HTML][HTML] Methods of liposomes preparation: formation and control factors of versatile nanocarriers for biomedical and nanomedicine application

D Lombardo, MA Kiselev - Pharmaceutics, 2022 - mdpi.com
Liposomes are nano-sized spherical vesicles composed of an aqueous core surrounded by
one (or more) phospholipid bilayer shells. Owing to their high biocompatibility, chemical …

[HTML][HTML] Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

M Ghezzi, S Pescina, C Padula, P Santi… - Journal of Controlled …, 2021 - Elsevier
Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …

Analytical characterization of liposomes and other lipid nanoparticles for drug delivery

Y Fan, M Marioli, K Zhang - Journal of pharmaceutical and biomedical …, 2021 - Elsevier
Lipid nanoparticles, especially liposomes and lipid/nucleic acid complexed nanoparticles
have shown great success in the pharmaceutical industry. Their success is attributed to …

Apolipoprotein E binding drives structural and compositional rearrangement of mRNA-containing lipid nanoparticles

F Sebastiani, M Yanez Arteta, M Lerche, L Porcar… - ACS …, 2021 - ACS Publications
Emerging therapeutic treatments based on the production of proteins by delivering mRNA
have become increasingly important in recent times. While lipid nanoparticles (LNPs) are …

Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents

A Angelova, VM Garamus, B Angelov, Z Tian… - Advances in colloid and …, 2017 - Elsevier
The present work highlights recent achievements in development of nanostructured
dispersions and biocolloids for drug delivery applications. We emphasize the key role of …

Structure and fate of nanoparticles designed for the nasal delivery of poorly soluble drugs

AR Clementino, G Pellegrini, S Banella… - Molecular …, 2021 - ACS Publications
Nanoparticles are promising mediators to enable nasal systemic and brain delivery of active
compounds. However, the possibility of reaching therapeutically relevant levels of …

[HTML][HTML] Structural characterization of biomaterials by means of small angle X-rays and neutron scattering (SAXS and SANS), and light scattering experiments

D Lombardo, P Calandra, MA Kiselev - Molecules, 2020 - mdpi.com
Scattering techniques represent non-invasive experimental approaches and powerful tools
for the investigation of structure and conformation of biomaterial systems in a wide range of …

[HTML][HTML] Liposomes characterization for market approval as pharmaceutical products: Analytical methods, guidelines and standardized protocols.

S Giordani, V Marassi, A Zattoni, B Roda… - … of Pharmaceutical and …, 2023 - Elsevier
Liposomes are nano-sized lipid-based vesicles widely studied for their drug delivery
capabilities. Compared to standard carries they exhibit better properties such as improved …

Liposomes loaded with phenolic extracts of Spirulina LEB-18: Physicochemical characterization and behavior under simulated gastrointestinal conditions

AR Machado, AC Pinheiro, AA Vicente… - Food research …, 2019 - Elsevier
Liposomes composed of rice (RL) and soybean (SL) lecithins were produced by reverse
phase evaporation and used for the encapsulation of phenolic extracts from Spirulina LEB …

Mixed cationic liposomes for brain delivery of drugs by the intranasal route: The acetylcholinesterase reactivator 2-PAM as encapsulated drug model

TN Pashirova, IV Zueva, KA Petrov… - Colloids and surfaces B …, 2018 - Elsevier
New mixed cationic liposomes based on L-α-phosphatidylcholine and
dihexadecylmethylhydroxyethylammonium bromide (DHDHAB) were designed to overcome …