Summary Unverricht‐Lundborg disease (ULD), progressive myoclonic epilepsy type 1
(EPM1, OMIM254800), is an autosomal recessively inherited neurodegenerative disorder …

В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

The progressive myoclonus epilepsies (PMEs) comprise a group of rare and heterogeneous
disorders defined by the combination of action myoclonus, epileptic seizures, and …

Purpose: To assess the efficacy and tolerability of chronic high‐frequency deep brain
stimulation (DBS) in adult patients with progressive myoclonic epilepsy (PME) syndromes …

Generalized motor seizures, usually tonic‐clonic, tonic‐vibratory, myoclonic or clonic, and
stimulus‐sensitive/action myoclonus are typical features of progressive myoclonus …

Objective To evaluate efficacy, tolerability, and safety of adjunctive brivaracetam (BRV) in
patients with Unverricht‐Lundborg disease (EPM 1). Methods Two prospective, multicenter …

Topiramate (TPM) is a widely-used drug for the treatment of epilepsy. It is useful for several
types of partial-onset and generalized-onset seizures, and is therefore considered a broad …

Progressive myoclonic epilepsy (PME) is a group of rare diseases characterized by
progressive myoclonus, cognitive impairment, ataxia, and other neurologic deficits. PME has …

Background: Progressive myoclonus epilepsies (PMEs) are a group of rare inherited
diseases featuring a combination of myoclonus, seizures and variable degree of cognitive …

The progressive myoclonic epilepsies (PMEs) represent a rare but devastating group of
syndromes characterized by epileptic myoclonus, typically action-induced seizures …