Enhancing permeation of drug molecules across the skin via delivery in nanocarriers: novel strategies for effective transdermal applications

YQ Yu, X Yang, XF Wu, YB Fan - Frontiers in bioengineering and …, 2021 - frontiersin.org
The transdermal route of administration provides numerous advantages over conventional
routes ie, oral or injectable for the treatment of different diseases and cosmetics applications …

Advances in transdermal insulin delivery

Y Zhang, J Yu, AR Kahkoska, J Wang, JB Buse… - Advanced drug delivery …, 2019 - Elsevier
Insulin therapy is necessary to regulate blood glucose levels for people with type 1 diabetes
and commonly used in advanced type 2 diabetes. Although subcutaneous insulin …

Ultrasound-responsive polymer-based drug delivery systems

P Wei, EJ Cornel, J Du - Drug delivery and translational research, 2021 - Springer
Ultrasound-responsive polymeric materials have received a tremendous amount of attention
from scientists for several decades. Compared to other stimuli-responsive materials (such as …

[HTML][HTML] Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery

SS Low, CN Lim, M Yew, WS Chai, LE Low… - Ultrasonics …, 2021 - Elsevier
Recent advances in ultrasound (US) have shown its great potential in biomedical
applications as diagnostic and therapeutic tools. The coupling of US-assisted drug delivery …

Current status and future potential of transdermal drug delivery

MR Prausnitz, S Mitragotri, R Langer - Nature reviews Drug discovery, 2004 - nature.com
The past twenty five years have seen an explosion in the creation and discovery of new
medicinal agents. Related innovations in drug delivery systems have not only enabled the …

Novel mechanisms and devices to enable successful transdermal drug delivery

BW Barry - European journal of pharmaceutical sciences, 2001 - Elsevier
Optimisation of drug delivery through human skin is important in modern therapy. This
review considers drug–vehicle interactions (drug or prodrug selection, chemical potential …

Transdermal drug delivery: overcoming the skin's barrier function

A Naik, YN Kalia, RH Guy - Pharmaceutical science & technology today, 2000 - Elsevier
The skin represents an extraordinary evolutionary feat. Not only does it physically
encapsulate the organism and provide a multifunctional interface between us and our …

Dermal and transdermal drug delivery systems: current and future prospects

MB Brown, GP Martin, SA Jones, FK Akomeah - Drug delivery, 2006 - Taylor & Francis
The protective function of human skin imposes physicochemical limitations to the type of
permeant that can traverse the barrier. For a drug to be delivered passively via the skin it …

Biomaterials in drug delivery and tissue engineering: one laboratory's experience

R Langer - Accounts of Chemical Research, 2000 - ACS Publications
This Account reviews our laboratory's research in biomaterials. In one area, drug delivery,
we discuss the development of materials that are capable of releasing macromolecules such …

Ultrasound-mediated transdermal drug delivery: mechanisms, scope, and emerging trends

BE Polat, D Hart, R Langer, D Blankschtein - Journal of controlled release, 2011 - Elsevier
The use of ultrasound for the delivery of drugs to, or through, the skin is commonly known as
sonophoresis or phonophoresis. The use of therapeutic and high frequencies of ultrasound …